Arizona Diamondbacks vs Cleveland Guardians Picks and Predictions for Saturday, August 1st, 2026

By: Cameron Ross Published 08/01/2026, 12:05 AM ET

Diamondbacks vs Guardians Game Information

The Arizona Diamondbacks continue a road trip up north Saturday night with a 7:15 PM matchup inside Progressive Field in Cleveland, OH, against the Cleveland Guardians. Arizona is 6 games above .500, currently the 2^nd-place team in the National League West, after a 3-game winning streak following the win in game 1 of this set on Friday. The Cleveland Guardians stay home Saturday, 2 games above .500 and are 3 games back in the American League Central, though they have lost 4 of the last 6 games. Stay in the action with our MLB Picks.

Diamondbacks Preview

The Arizona Diamondbacks offense has a .242 batting average this season, scoring 492 runs on 883 hits. Arizona has a .313 OBP and a .393 team slugging percentage. The Diamondbacks pitching has been their biggest issue with a 4.20 ERA, but they have allowed just 8 runs across their current 3-game winning streak. Ildemaro Vargas leads the Arizona offense this season with a .275 batting average. Ketel Marte has a .253 batting average and leads the team with 19 home runs and 61 RBI.

Guardians Preview

The Cleveland Guardians have a .230 batting average this season, scoring 432 runs on 837 hits. Cleveland has a .310 OBP and a .369 team slugging percentage. The Cleveland pitching staff has been their biggest strength, with a 3.73 team ERA this season. Chase DeLauter leads the Cleveland offense this season with a .280 batting average and 51 RBIs. Kyle Manzardo has a .211 batting average and leads the team with 13 home runs.

Diamondbacks vs Guardians Pitching Matchup

Kohl Drake will be on the mound Saturday for Arizona. Drake is 0-0 this season with a 5.00 ERA through only 9 innings of work. Parker Messick will be on the bump for the Guardians, looking to build on his success. Messick is 8-6 overall with a 2.59 ERA across 125.1 innings of work.

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Diamondbacks vs Guardians Pick

The Cleveland Guardians enter Saturday desperately needing a win after Friday’s loss. Cleveland has the pitching advantage in Game 2 and should benefit from playing in front of its home crowd. Look for the Guardians to bounce back and move closer to the top of the AL Central following the win in Game 2 of this series.

Pick: Cleveland Guardians -164
Secondary: Over 8
Lean: Chase DeLauter Over 1.5 Bases

Final Score Prediction: Cleveland Guardians win 7-3.

Game Written Before completion of the game on Friday.