Arizona Diamondbacks vs San Francisco Giants Picks and Predictions for Monday, September 8, 2025

By: David Anicetti Published 09/08/2025, 12:25 AM ET

The Arizona Diamondbacks visit Oracle Park to face the San Francisco Giants on Monday night at 9:45 PM ET, with FS1 providing coverage. Arizona comes in at 72-71 and 34-38 on the road, while San Francisco is 72-70 with a 35-34 home record. With both teams hovering around .500 and in the wild-card mix, our free MLB picks is just what is needed to make a clear and concise betting decision.

Arizona Diamondbacks Preview

Arizona’s lineup has been led by Geraldo Perdomo and Corbin Carroll. Perdomo is hitting .286 with a .384 OBP and a team-best 91 RBIs, while Carroll has 30 homers, 74 RBIs, and 24 steals. The Diamondbacks are batting .250 with 197 homers and 707 runs scored. The Diamondbacks have won four of their last five.

Nabil Crismatt starts on the mound for Arizona, carrying a 2-0 record and 2.14 ERA across 21 innings. Crismatt has allowed 22 hits with 14 strikeouts and six walks. The Diamondbacks’ staff overall has a 4.43 ERA and 1.32 WHIP, with opponents hitting .253. For a club that leans on its bats to win, Crismatt’s ability to limit runs and then hand off to the bullpen is a key.

San Francisco Giants Preview

The Giants are led by Willy Adames and Heliot Ramos. Adames has 27 home runs, 78 RBIs, and a .229 average, while Ramos leads with a .269 batting average and 145 hits. San Francisco has produced 615 runs with 152 homers, though inconsistency at the plate has kept them near or below .500. The Giants have dropped three of their last five, and run support for Logan Webb will be critical against a tough Arizona lineup.

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San Francisco turns to Webb, who owns a 13-9 record with a 3.17 ERA and 1.23 WHIP over 178.2 innings. Webb has 194 strikeouts against 39 walks, making him one of the most dependable arms in the NL. The Giants’ staff as a whole holds a 3.76 ERA and 1.28 WHIP, keeping opponents to a .246 average. Webb’s ability to pitch deep into games helps conserve the San Francisco bullpen, which sees more action than it should.

Diamondbacks vs Giants Prediction

Webb’s durability and strikeout ability give San Francisco the advantage at home, though a low-scoring game is expected with both starters in form of late. Final Score Prediction: San Francisco Giants win 4-2.