Boston Red Sox vs Athletics Picks and Prediction for Wednesday September 10 2025
Red Sox Preview
Sutter Health Park will play host to a Wednesday afternoon MLB clash between the Boston Red Sox and the Athletics. Be ready for the baseball season with all of our MLB predictions. The Red Sox (81-65) have split their first 74 road games and are sitting in second place in the AL Wild Card standings. Last night, Romy Gonzalez and Rob Refsnyder each homered to lead Boston to a 6-0 road victory against the Athletics.
Rookie left-hander Payton Tolle (0-1 7.56 ERA) will make his third career major league start for the Red Sox. Last time out, Tolle lasted just three innings and surrendered five runs during a 10-5 road loss against Arizona.
Athletics Preview
The Athletics have dropped eight of their previous 11 games and are trapped in the AL West Division cellar. During Tuesday’s home loss, the Athletics went 1-for-10 with runners in scoring position and left 11 men on base. SP Jeffrey Springs (10-11) was roughed up for five runs across five frames and took the loss for the Athletics (66-80), who fell to 29-42 at home.
Twenty-four year old righty Mason Barnett (1-1 9.00 ERA) will make his third career major league start for the Athletics. In his last start, Barnett (5 IP) gave up three runs and fanned eight batters during a 10-4 road triumph against Los Angeles.
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Red Sox vs Athletics Pick
Boston OF Roman Anthony has landed on the 10-day injured list with an oblique strain and could miss the next 4-6 weeks. Through 146 games, Boston ranks 8th in OPS and 4th in runs scored. For the season, the Athletics rank 6th in OPS and 12th in runs scored. Take the Red Sox to win on the road. Final Score Prediction, Boston Red Sox win 6-4.
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