Boston Red Sox vs Detroit Tigers Picks and Predictions for Monday, May 4, 2026

By: Cameron Ross Published 05/04/2026, 01:10 AM ET

Red Sox vs Tigers Game Information

The Boston Red Sox will begin a road trip Monday night with game 1 of 3 inside Comerica Park in Detroit, MI, at 6:40 PM against the Detroit Tigers. Boston is struggling this season, coming into Monday with 13 wins and 21 losses, having lost 4 of the last 5, including 2 in a row. The Detroit Tigers stay home Monday night, with 18 wins and 17 losses, after winning 3 of the last 4, including the last 2, after a 6-run home victory against the Texas Rangers. Keep up with our MLB Picks.

Red Sox Preview

Offensively, Boston has been lackluster this season, with a .235 batting average. The Red Sox have scored 129 runs on 258 hits. The Boston power has been nonexistent with a .351 team slugging percentage and only 22 home runs this season. Boston's pitching has been horrendous, with a 4.29 team ERA, and the team has allowed 20 runs over its last 4 losses. Wilyer Abreu leads the Boston offense this season with a .298 batting average. Willson Contreras has a .280 batting average and leads the Red Sox with 7 home runs and 21 RBI's.

Tigers Preview

The Detroit Tigers offense has been solid this season, with a .251 batting average. The Tigers have scored 151 runs on 285 hits. Detroit has a .333 OBP and a .406 team slugging percentage. Detroit pitching has carried the team with a 3.90 ERA, and the Tigers have allowed 4 runs over the last 3 wins. Kevin McGonigle leads the Detroit offense this season with a .315 batting average. Kerry Carpenter has a .213 batting average and leads Detroit with 6 home runs.

Red Sox vs Tigers Pitching Matchup

Payton Tolle will take the mound Monday night for Boston in Game 1 of this series. This season, Tolle is 0-1 with a 3.38 ERA across 10.2 innings of work. Tarik Skubal will counter for Detroit with a 3-2 record and a 2.70 ERA across 43.1 innings of action

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Red Sox vs Tigers Sox Pick

Detroit is the much better team in this matchup and has the edge on both sides of the ball. Detroit has a stronger offense and its home fans behind it. Look for Detroit to continue its winning ways Monday night as they extend their winning streak with a home victory against the Boston Red Sox.

Pick: Detroit Tigers -1.5
Secondary: Over 7
Lean: Dillon Dingler Over. 5 RBIS

Final Score Prediction: Detroit Tigers win and cover 9-2.