Boston Red Sox vs Pittsburgh Pirates Picks and Prediction for Sunday August 16 2026

By: Eddie Kline Published 08/16/2026, 01:20 AM ET

Red Sox Preview

Scenic PNC Park will play host to a Sunday afternoon MLB interleague clash between the Boston Red Sox and the Pittsburgh Pirates. Be ready for the baseball season with all of our MLB predictions. The Red Sox (65-58) have won 37 of their first 64 road games and are sitting comfortably in second place in the American League Wild Card standings. Last night, OF Wilyer Abreu went 3-for-4 with a run scored and an RBI to spark Boston to a 4-0 road victory against Pittsburgh.Β 

Twenty-nine year old southpaw Patrick Sandoval (1-1 3.30 ERA) will make his seventh start of the season for the Red Sox. Last time out, Sandoval (6 IP) was roughed up for eight hits and four runs during a 5-3 road loss against Toronto.

Pirates Preview

The Pittsburgh Pirates have dropped eight of their previous 11 games and are six games back in the race for the final National League Wild Card spot. During Saturday’s home loss, Pittsburgh batters managed just six hits and were retired by strikes on ten occasions. SP Jared Jones (2-5) allowed one run in five innings and was the hard luck loser for the Pirates (60-65), who fell to 31-32 at home.Β 

The Pirates will give the nod to reigning National League Cy Young Award winner Paul Skenes (9-11 3.88 ERA) in the series finale. Through 134 plus innings, Skenes ranks seventh in the majors with 166 strikeouts and sports a solid 1.12 WHIP.Β 

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Red Sox vs Pirates Pick

Boston OF Roman Anthony (finger) is getting close to starting a rehab assignment and hopes to return to the lineup later this month. Through 123 games, Boston ranks 14th in OPS and 16th in runs scored. For the season, Pittsburgh ranks 4th in OPS and 3rd in runs scored. Take the under. Final Score Prediction, Pittsburgh Pirates win 4-3.Β 

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