Chicago White Sox vs New York Yankees Pick and Prediction for Thursday September 25, 2025

By: Cameron Ross Published 09/25/2025, 12:30 AM ET

White Sox vs Yankees Game Information

Yankee Stadium will host a matchup Thursday night between the Chicago White Sox and the New York Yankees at 7:05 PM. Chicago was the worst team in the American League, more than 40 games below .500 on the year, riding a lengthy losing streak into this matchup. The New York Yankees stay home Thursday night in pursuit of the AL East division title, currently riding a 4-game winning streak. Stay in the action with our MLB Picks.

White Sox Preview

Offensively, Chicago has been well below average this season, with a .232 batting average. The White Sox have scored only 620 runs on 1208 hits. The Chicago pitching has been horrendous with a 4.22 team ERA. Lenyn Sosa leads the Chicago offense this season with a .258 batting average, 21 home runs, and 71 RBI's.

Yankees Preview

Offensively, New York has carried their weight this season with a .250 batting average. The Yankees have scored 819 runs and 1338 hits. The New York pitching staff has fared well this season, boasting a 3.96 team ERA. Aaron Judge does everything for the New York offense, leading the team with a .325 batting average, 49 home runs, and 105 RBIs.

White Sox vs Yankees Pitching Matchup

Davis Martin will take the mound Thursday for Chicago. Martin has seven wins and 10 losses and a 4.03 ERA across 138.1 innings of work. Carlos Rodon will take the mound Thursday in the final game of this set for New York. This season, Rodon has seventeen wins and 9 losses and a 3.04 ERA across 189.1 innings of work.

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White Sox vs Yankees Pick

The Yankees are the far better team in this game and will roll on Thursday. New York is still in the hunt for the division. Look for New York to dominate Thursday night at home as they get the win and cover, inching closer to the top spot in the AL East.

Pick: New York Yankees -1.5

Secondary: Β Over 8.5

Lean: Aaron Judge Over 1.5 Bases

Final Score Prediction: New York Yankees win and cover 9-4.Β Β 

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