Cincinnati Reds vs Milwaukee Brewers Picks and Predictions for Sunday, September 28, 2025

By: Cameron Ross Published 09/28/2025, 01:10 AM ET

Reds vs Brewers Game Information

The Cincinnati Reds will conclude the 2025 season on Sunday with the game inside American Family Field at 3:10 PM against the Milwaukee Brewers. Cincinnati has fared well enough this season, entering the final days of the year, as it fights for a playoff seeding. The Milwaukee Brewers are the top team in Major League Baseball and will look to finish the year strong as they prepare for a deep playoff run. Stay in the action with our MLB Picks.

Reds Preview

Offensively, Cincinnati has been mediocre this season, with a .245 batting average. The Reds have scored 704 runs on 1309 hits. The Reds power has been resounding this year with 164 home runs and a .391 Team slugging percentage. The Cincinnati pitching has been solid enough this season with a 3.88 team ERA. Spencer Steer leads the way for Cincinnati with 21 home runs this season. Gavin Lux has posted a team high of .269 batting average, and Elly De La Cruz leads the team with 85 RBIs on the year.

Brewers Preview

The Milwaukee Brewers are the best team in baseball and have compiled a .260 batting average this season to score 797 runs on 1406 hits. The Milwaukee pitching has been top tier this season as well, with a 3.61 team ERA. Sal Frelick is the top bat in the Milwaukee lineup this season with a .291 batting average. Christian Yelich leads the team with 29 home runs and 102 RBIs this season.

Diamondbacks vs Padres Pitching Matchup

Brady Singer will take the mound for Cincinnati in the final game of the year. Singer has fourteen wins and 11 losses this season to go along with a 3.95 ERA across 166.1 innings of work. Freddy Peralta will counter for Milwaukee on the final day of the year. Peralta has seventeen wins and six losses this season with a 2.68 ERA in just over 174 innings of action.

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Reds vs Brewers Pick

The Milwaukee Brewers have nothing left to play for heading into the final day of the year and will likely rest a ton of guys. Cincinnati, on the other hand, is still fighting for a playoff spot and must do the work in this game. Take the Reds to leave it all on the field as they pick up a win on the final day of the season in hopes of punching their ticket into October.

Pick: Cincinnati RedsΒ 

Secondary: Β UnderΒ 

Lean: Elly De La Cruz Over 1.5 Bases

Final Score Prediction: Cincinnati Reds win 4-2.

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