Cincinnati Reds vs St. Louis Cardinals Picks and Predictions for Saturday, July 25, 2026

By: Cameron Ross Published 07/25/2026, 12:45 AM ET

Reds vs Cardinals Game Information

The Cincinnati Reds continue a road trip Saturday night with a 7:15 PM Game inside Busch Stadium in St. Louis, MO, against the Saint Louis Cardinals. Cincinnati is 6 games below .500 this season, having won 4 of the last 5, including 3 in a row after the win in Game 1 of this set. The Saint Louis Cardinals stay home Saturday, 1 game above .500, but they have dropped 4 of the last 5, including 2 in a row. Stay up to date with our MLB Picks.

Reds Preview

The Cincinnati Reds have a .230 batting average this season, scoring 423 runs on 777 hits. Cincinnati has a .309 OBP and a .400 team slugging percentage. The Reds pitching has struggled this year with a 4.56 team ERA. Elly De La Cruz leads Cincinnati with a .276 batting average. Sal Stewart has a .251 batting average and leads the team with 21 home runs and 75 RBIs.

Cardinals Preview

The St. Louis Cardinals have a .241 batting average this season, scoring 454 runs on 823 hits. St. Louis has a .317 OBP and a .384 team slugging percentage. The Cardinals pitching has been mediocre with a 4.12 team ERA this year. Jordan Walker leads the St. Louis offense with a .288 batting average, 22 home runs, and 77 RBIs.

Reds vs Cardinals Pitching Matchup

Hunter Greene will take the mound Saturday for Cincinnati, looking to settle in after a difficult start to his season. Greene is 2-1 with a 6.06 ERA Β through 16.1 innings. Andre Pallante will counter for St. Louis, looking to earn his 11th victory. Pallante is 10-6 this year with a 4.02 ERA through 105.1 innings of work

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Reds vs Cardinals Pick

The St. Louis Cardinals have the more reliable starting pitcher and will take advantage of playing at home Saturday. Look for the Cardinals offense to do the work Saturday, leading St. Louis to a divisional victory.

  • Pick: St. Louis Cardinals
  • Secondary: Over
  • Lean: Jordan Walker Over 1.5 Total Bases

Final Score Prediction: St. Louis Cardinals win 6-4.

Β Game Written Before completion of the game on Friday.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+