Cleveland Guardians vs Boston Red Sox Picks and Prediction for Tuesday September 2 2025

By: Eddie Kline Published 09/02/2025, 01:00 AM ET

Historic Fenway Park will play host to a Tuesday night MLB clash between the Cleveland Guardians and the Boston Red Sox. Be ready for the baseball season with all of our MLB predictions. The Guardians (68-68) have dropped six of their last ten games and are four games back in the race for the final AL Wild Card spot. On Monday, leadoff hitter Steven Kwan collected three of Cleveland’s eight hits during a 6-4 road loss against Boston.

Guardians Preview

Twenty-six year old righty Slade Cecconi (5-6 4.41 ERA) will head to the hill for the Guardians in this contest. Through 102 innings of work, Cecconi has surrendered 20 long balls and owns a respectable 1.26 WHIP.The Boston Red Sox have won 43 of their first 70 home games and are sitting in second place in the AL Wild Card standings. During Monday’s home victory, Boston SS Trevor Story went 3-for-4 with a home run and drove in a pair of runs. Rookie OF Roman Anthony added two hits and scored a run for the Red Sox, who improved to 77-62 overall.

Red Sox Preview

Boston manager Alex Cora will give the nod to talented left-hander Garrett Crochet (14-5 2.40 ERA) on Tuesday. Last time out, Crochet (6 IP) allowed two runs and retired seven batters by strikes during a 3-2 road victory against Baltimore.

Red Sox vs Guardians Pick

Boston OF Wilyer Abreu (calf) has resumed running sprints and should rejoin the lineup this week. Through 136 games, Cleveland ranks 29th in OPS and 28th in runs scored. For the season, Boston ranks 9th in OPS and 5th in runs scored. Take the under. Final Score Prediction, Boston Red Sox win 5-1.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+