Colorado Rockies vs Cincinnati Reds Pick & Prediction for Tuesday, April 28, 2026

By: Ricky Mackenzie Published 04/28/2026, 01:45 AM ET

Rockies Preview

Colorado enters this matchup after a strong 3-0 win over the Mets, a result that showed rare clean pitching and timely offense from a club that has struggled to stay consistent. Get our free MLB Picks all season long! The Rockies are still just 13-16 on the season, but winning six of their last ten gives them some momentum heading into Cincinnati. Tomoyuki Sugano gets the ball after posting a 2-1 record with a 3.42 ERA.

Reds Preview

Cincinnati comes in off an ugly 8-3 home loss to Detroit, where the pitching staff could not slow the Tigers’ offense. Even with that setback, the Reds remain 18-10 and one of the better teams in the National League. Chase Burns has been excellent early, carrying a 2-1 record with a sharp 2.57 ERA and strong strikeout numbers through 28 innings.

Reds vs Rockies Pitching Matchup

The pitching matchup is the biggest edge for Cincinnati, especially at home where Burns can attack aggressively early. Colorado has shown flashes offensively, but this lineup still struggles for sustained production away from home. The Reds should also benefit from better bullpen depth if this game stays tight into the late innings.

Reds vs Rockies Pick

The Reds are listed as heavy -200 favorites with the total set at 8.5, which reflects both the home-field advantage and the trust in Burns. Colorado can stay competitive if Sugano limits walks and keeps the ball in the park, but Cincinnati’s offense has more upside over nine innings.

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Colorado is playing better lately, but this still feels like a difficult spot against a stronger and more complete Reds roster. Cincinnati should respond well after the Detroit loss and let Burns set the tone early. Expect the Reds to control the pace and finish the job at home. Final Score Prediction, Cincinnati Reds win 5-2.