Detroit Tigers vs Cleveland Guardians Pick and Prediction for Thursday September 25, 2025
Tigers vs Guardians Game Information
The Detroit Tigers continue a road trip Thursday with game three of three in Cleveland for a game against the Cleveland Guardians at Progressive Field. Detroit comes into this game well above .500 but has struggled of late after blowing a huge lead in the division. The Cleveland Guardians stay at home on Thursday as one of the hottest teams in baseball, having caught the Detroit Tigers in pursuit of the division title. Stay in the action with our MLB Picks.
Tigers Preview
Offensively, Detroit has been top-tier this season, with a .241 batting average. The Tigers have scored 745 runs on 1307 hits. The Detroit pitching has been stout as well, with a 3.9 team ERA, but Detroit has allowed 30 total runs over its last five losses. Riley Greene leads the Detroit offense this season with a .261 batting average, 35 home runs, and 110 RBI's.
Guardians Preview
The Cleveland Guardians have been mediocre offensively this season, with a .26 batting average, having scored just 621 runs on 1164 hits overall. The Cleveland pitching has been phenomenal this season, with a 3.69 team ERA. Jose Ramirez is the top bat in the Cleveland lineup, leading the way with a .282 batting average, 30 home runs, and 82 RBI's this season.
Tigers vs Guardians Pitching Matchup
Detroit has yet to name a starter for Thursday's game and could rely heavily on its bullpen in the final game of this series. Parker Messick will be on the mound for Cleveland on Thursday. In the year, Mesnick has three wins and 0 losses, accompanied by a 2.08 ERA across 34.2 innings of action.
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Tigers vs Guardians Pick
These 2 teams are battling it out for playoff seeding and a division title. Cleveland is one of the hottest teams in the league, and Detroit has completely fallen apart. Cleveland will have the better arm on the bump in this game, as Detroit has yet to name a starter. Take the Guardians to continue to win Thursday night at home.
Pick: Cleveland Guardians -1.5
Secondary: Over
Lean: Jose Ramirez Over 1.5 Bases
Final Score Prediction: Cleveland Guardians win and cover 8-3.
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