Detroit Tigers vs Miami Marlins Picks and Predictions for Friday, September 12, 2025

By: David Anicetti Published 09/12/2025, 12:00 AM ET

Tigers vs Marlins Game Information

The Detroit Tigers play the opening game of a three-game series on the road Friday versus the Miami Marlins at loanDepot Park with a 7:10 PM ET first pitch. The Tigers are 84-62 (38-33 away) and just routed the Yankees 11-1 and 12-2. Miami sits 67-79 (33-41 home) after a split with Washington, including an 8-3 win last time out. Detroit starts Tarik Skubal (13-4, 2.10 ERA, 0.86 WHIP, 222 Ks, 28 BBs, in 180.0 innings) on the mound while Miami counters with Sandy Alcantara (8-12, 5.67 ERA, 1.32 WHIP in 154.0 innings). Be prepared to wrap up the MLB season on a winning streak with our free MLB Picks.

Detroit Tigers Preview

Detroit’s lineup has been above average all season. The Tigers are hitting .251/.320/.423 with 184 home runs and 718 runs scored, and have been especially dangerous when Riley Greene is performing well. Greene leads with 33 home runs, 107 RBI, and a .509 slugging percentage, while Spencer Torkelson (28 HRs, .458 slugging percentage) and Kerry Carpenter (.514 slugging percentage) give Detroit multiple behind Greene.

On the mound, Detroit’s pitching staff owns a 3.86 ERA and 1.23 WHIP, and Skubal’s numbers - an elite-level strikeout rate (222 Ks) with just 28 walks, will make it difficult for Miami’s hitters to catch up to the left-hander’s fast ball and different pitches. If Skubal limits his walks, Miami will have its share of problems at the plate and will need to rely on its starter, Alcantara, to hold the Detroit hitters.

Miami Marlins

The Marlins’ season slash line sits at .250/.315/.393 with 139 homers, so they rely more on contact and timely extra-base hits. Kyle Stowers has done the most damage at the plate (.288/.368/.544, 25 home runs, 73 RBI), and Xavier Edwards leads in hits with 147 and a .282 average. Agustin Ramirez’s 19 homers give Miami additional power at the plate.

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The problem all season has been on the mound. Miami has a team ERA of 4.78 with a 1.33 WHIP, and Alcantara’s 53 walks have helped opponents extend innings. Against a patient Detroit lineup, early base on balls could hurt Miami’s chances. Miami needs Alcantara’s pitches to find the strikeout and rely on the defense to make plays in the field.

Detroit Tigers vs Miami Marlins Prediction

Skubal’s accuracy on the mound matches up well with a below-average Miami lineup, and Detroit’s lineup has been more consistent at the plate. The Tigers have too many ways to score, and a closer game down the stretch will favor the Tigers’ bullpen over that of Miami. Final Score Prediction: Detroit Tigers win 6-2.