Houston Astros vs Chicago White Sox Picks and Predictions for Sunday, July 26, 2026

By: Cameron Ross Published 07/26/2026, 01:00 AM ET

Astros vs White Sox Information

The Houston Astros stay on the road Sunday afternoon with a 2:10 PM game inside Rate Field in Chicago against the Chicago White Sox. Houston is 2 games below .500 this season coming into Sunday, riding a long winning streak after taking both games in this series thus far. The Chicago White Sox stay home Sunday, 5 games above .500 and currently the top team in the American League Central, but they have lost 3 of the last 5 games. Stay in the action with our MLB Picks.

Astros Preview

The Houston Astros have a .243 batting average this season, and have scored 482 runs on 856 hits. Houston has a .316 OBP and a .414 team slugging percentage. The Astros pitching has struggled, however, with a 4.71 team ERA this year. Yordan Alvarez leads the Houston offense with a .325 batting average, 34 home runs, and 77 RBIs.

White Sox Preview

The Chicago White Sox have a .240 batting average this season and have scored 488 runs on 817 hits. Chicago has a .318 OBP and a .408 team slugging percentage. The White Sox pitching has been solid with a 4.13 team ERA this year. Sam Antonacci leads Chicago with a .278 batting average. Colson Montgomery leads the team with 24 home runs, while Miguel Vargas has a team-high 61 RBIs.

Astros vs White Sox Pitching Matchup

Ronel Blanco will take the mound Sunday for Houston, making his second start since returning from Tommy John surgery. Blanco is 0-0 with a 7.71 ERA through 4.2 innings of work. Erick Fedde will counter for Chicago, looking to get back to .500. Fedde is 5-6 this year with a 4.16 ERA through 93 innings of work.

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Astros vs White Sox Pick

The Houston Astros have won 4 consecutive games and will again have the edge Sunday. Look for the Astros to further their success Sunday against a struggling team. The Astros offense will lead the way on Sunday against a lackluster pitcher, extending their winning streak with a win in game 3 of this series.

Pick: Houston Astros -108
Secondary: Over9.5
Lean: Yordan Alvarez Over 1.5 Bases

Final Score Prediction: Houston Astros win 8-4.