Houston Astros vs Cincinnati Reds Picks and Prediction for Saturday May 9 2026

By: Eddie Kline Published 05/09/2026, 01:40 AM ET

Astros Preview

The Great American Ball Park will be the scene for a Saturday afternoon MLB interleague clash between the Houston Astros and the Cincinnati Reds. Be ready for the baseball season with all of our MLB predictions. The Astros (16-23) have dropped 13 of their first 20 road games and are four games off the pace in the AL West Division race. Last night, Yordan Alvarez and Zach Dezenzo each went deep to power Houston to a 10-0 road victory against Cincinnati. Zach Cole added a three-run blast in the ninth inning to seal the deal for the Astros.

Twenty-six year old righty Spencer Arrighetti (4-0 1.96 ERA) is off to a splendid start to the year for the Astros. Through 23 innings of work, Arrighetti has struck out 25 batters and owns a respectable 1.35 WHIP.

Reds Preview

The Cincinnati Reds are looking to snap an eight-game losing streak and have plummeted into the NL Central Division basement. During Friday’s home loss, Cincinnati batters managed just five hits and went 1-for-6 with runners in scoring position. SP Nick Lodolo (0-1) gave up four runs in five plus innings and took the loss for the Reds (20-19).

The Reds will counter with flame-throwing righty Chase Burns (3-1 2.20 ERA) in the middle game of this series. Last time out, Burns fired seven shutout frames and fanned seven batters during a 1-0 road loss against Pittsburgh.

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Astros vs Reds Pick

Cincinnati 3B Eugenio Suarez is currently on the 10-day injured list with an oblique injury and is eligible to return next week. Through 39 games, Houston ranks 5th in OPS and 6th in runs scored. For the season, Cincinnati ranks 23rd in OPS and 22nd in runs scored. Take the Reds to win at home. Final Score Prediction, Cincinnati Reds win 5-3.