Houston Astros vs Colorado Rockies Picks and Prediction for Monday, April 6, 2026

By: David Anicetti Published 04/06/2026, 12:05 AM ET

The Houston Astros visit the Colorado Rockies at Coors Field on Monday, April 6, at 8:40 PM ET on MLB.TV. Houston is 6-3, sitting first in the AL West, while Colorado is 2-6 and last in the NL West after just a handful of games. The Astros have won four of their last five games, while the Rockies have dropped four of five. Find value with our free MLB picks.

Houston Astros Preview

Houston has opened the season with one of the more productive offenses in baseball, hitting .283 as a team with a .391 on-base percentage and .479 slugging percentage. The Astros have scored 60 runs through nine games, showing the ability to generate consistent run production rather than relying on isolated scoring bursts. That balance has been key in building early wins.

Yordan Alvarez has been the standout, hitting .423 with three home runs and eight RBI, while Christian Walker is hitting .344 with nine RBI. Jose Altuve has also contributed with a .321 average and a .500 on-base percentage, giving Houston multiple reliable hitters at the top and middle of the lineup. This depth allows Houston to maintain pressure across innings.

Injuries: Glenn Otto, Day-To-Day, Isaac Paredes, Bereavement, Enyel De Los Santos, 15-Day IL, Bennett Sousa, 15-Day IL, Josh Hader, 15-Day IL

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Colorado Rockies Preview

Colorado has struggled offensively to begin the season, hitting .217 with a .263 on-base percentage and .319 slugging percentage. The Rockies have scored just 26 runs in eight games and have struck out 91 times, which has limited their ability to sustain rallies. This has made it difficult to stay competitive in their first eight games of the season.

Ezequiel Tovar leads the team with a .294 average and five RBI, while TJ Rumfield has been one of the few consistent hitters at .360. Troy Johnston has added some power with one home run, but overall production throughout the lineup has been limited. Colorado has not shown the ability to string together hits consistently.

Injuries: Jared Thomas, DTD, Charlie Condon, DTD, Jose Quintana, 15-Day IL, McCade Brown, 60-Day IL, Case Williams, 60-Day IL

Pitching Matchup

Houston Astros – Hunter Brown

Brown is 1-0 with a 0.84 ERA and 1.03 WHIP over 10.2 innings. He has allowed just five hits while striking out 17 and issuing six walks in two starts.

Colorado Rockies – Ryan Feltner

Feltner has a 0.00 ERA and 0.67 WHIP over 3.0 innings. He has allowed one hit with four strikeouts and one walk in one appearance.

Houston Astros vs Colorado Rockies Prediction

Houston has a clear advantage in this matchup with a stronger lineup and a more proven starting pitcher. The Astros have shown consistent offensive production through multiple hitters, while Colorado has struggled to generate runs through its first eight games. Brown’s ability to limit contact gives Houston an edge against a lineup that has already struggled with strikeouts. Colorado would need improved production at the plate and score early against Brown to stay competitive, but that will be difficult against Houston’s ace. The Astros will continue their balanced approach at the plate and limit baserunners, resulting in Houston controlling the game from the early innings. Final Score Prediction: Houston Astros win 6-2.