Houston Astros vs Los Angeles Angels Picks and Predictions for Wednesday, June 10, 2026

By: Cameron Ross Published 06/10/2026, 12:50 AM ET

Astros vs Angels Game Information

The Houston Astros stay on the road Wednesday night for a 9:38 PM matchup at Angel Stadium in Anaheim against the Los Angeles Angels. Houston is below .500 this season coming into Tuesday night. The Los Angeles Angels stay at home on Tuesday, well below .500, and are currently the last-place team in the American League West. Keep up with our MLB Picks.

Astros Preview

The Houston Astros have a .246 batting average this season and have scored 312 runs on 562 hits. Houston has a .321 OBP and a .412 team slugging percentage. Houston's pitching has been the team's biggest issue this season, with a 4.89 team ERA. Yordan Alvarez leads the Houston offense this season with a .311 batting average and 22 home runs. Christian Walker has a .252 batting average and leads the Astros with 48 RBI's.

Angels Preview

Offensively, Los Angeles has been mediocre this season with a .233 batting average. They have scored 295 runs on 522 hits. Los Angeles has a .315 OBP and a .3817 slugging percentage. The Los Angeles pitching staff has been shaky this season, with a 4.79 team ERA, and the Angels have allowed 15 runs across their last 3 losses. Nolan Schanuel leads the Los Angeles offense with a .253 batting average. Mike Trout has a .222 batting average and leads the team with 14 home runs. Jo Adell has a .239 batting average and leads the way with 37 RBI's.

Astros vs Angels Pitching Matchup

Peter Lambert will be on the mound for the Astros on Thursday, looking to continue his success. Lambert is 5-4 with a 3.55 ERA this year, over 50.2 innings. Reid Detmers will counter for the Angels. Detmers is struggling this year with a 2-5 record and a 4.26 ERA through 74 innings.

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Astros vs Angels Pick

The Astros are the better team playing the better baseball in this matchup. Houston has the better offense and the better arm on the bump Thursday. Take the Astros to do the work and win on the road in Game 3 of this set.

Pick: Houston Astros +102
Secondary: Over 8.5
Lean: Yordan Alvarez Over 1.5 bases

Final Score Prediction: Houston Astros win 7-4.

Game Written Prior to completion of game on Tuesday.