Kansas City Royals vs Cleveland Guardians Picks and Prediction for Thursday September 11 2025

By: Cameron Ross Published 09/11/2025, 12:55 AM ET

Royals vs Guardians Game Information

The Kansas City Royals stay on the road Thursday with another game in Cleveland as they match up with the Cleveland Guardians in Progressive Field at 7:15 PM. Kansas City is 2 games above .500 on the year, currently 10 games back in the American League Central, having dropped three of the last five overall. The Cleveland Guardians stay home on Thursday as the number two team in the American League Central following the loss in Game 1 of this set. Stay in the action with our MLB Picks.

Royals Preview

Bobby Witt Jr. has been an offensive leader this season for Kansas City, leading the team with a .295 batting average. Vinnie Pasquantino leads the Kansas City offense this season with 29 home runs and 100 RBIs. As a unit, Kansas City has a .244 batting average and has scored 553 runs on 1176 hits.

Guardians Preview

Jose Ramirez is the offensive leader this season for Cleveland with a .287 batting average, 28 home runs, and 76 RBIs. As a team, Cleveland has been mediocre this season, with a .226 batting average. The Guardians have scored 564 runs on 1065 hits. The Guardians bullpen has been the team's biggest strength with the 3.87 team ERA.

Royals vs Guardians Pitching Matchup

Stephen Kolek will be on the mound Thursday for Kansas City. In the year, Kolek has five wins and five losses and a 3.88 ERA across 92.2 innings of work. Gavin Williams will counter for Cleveland with ten wins and five losses this season and a 3.17 ERA.

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Royals vs Guardians Pick

Both teams are fighting for playoff positioning, but Cleveland will have the edge in this matchup. Look for the Guardians pitching edge and home fans on Thursday. Take the guardians to do the work as they get the win at home to inch closer to a potential playoff berth.

Pick: Cleveland Guardians -130

Lean: Jose Ramirez RBI

Final Score Prediction: Over 7.5