Los Angeles Angels vs Seattle Mariners Picks and Prediction for Friday September 12 2025

Mariners vs Angels Game Information

The Seattle Mariners continue their home series with the Los Angeles Angels in town on Friday. The Mariners are a heavy -165 home favorite and the total is set at 7.5 runs. The Angeles beat the Mariners 4-1 in their last meeting back in July. Check out all of our experts MLB Free Picks.

Seattle Mariners Preview

The Seattle Mariners entered this series on Thursday riding a five game win streak. The Mariners are 44-27 at home and have won six of their last ten games. Seattle swept St. Louis in their last series. The Mariners outscored the Cardinals 13-7 in that series. Seattle is averaging 8.3 hits per game.

Luis Castillo will make his 30th start on the mound for the Mariners. Castillo is 9-8 on the season with 161.1 innings pitched. Castillo has 144 strikeouts and carries a 3.85 ERA. Castillo pitched 6 innings in his last start allowing 4 hits and 1 run.

Los Angeles Angels Preview

The LA Angels also entered this series riding a win streak. The Angels won two straight entering Thursday's matchup. Los Angeles has won five of their last ten games and carry a losing road record. The Angels are averaging 7.6 hits per game.

Yusei Kikuchi will make his 31st  start on the mound for the LA Angels. Kikuchi is 6-11 on the season with 161.2 innings pitched. Kikuchi has 163 strikeouts and carries a 4.18 ERA. Kikuchi pitched 2 innings in his last start allowing 6 hits and 7 runs.

Seattle Mariners vs Los Angeles Angels Pick and Predictions:

Final Score Prediction: Seattle Mariners win 6-3.

Never Tried Picks and Parlays? Now Is Your Chance

• Get your first daily picks package for ONLY $1 using coupon code BUCK
• If the pick loses, we credit your account with 3 Flex Picks
• If the pick wins, we still give you 1 Flex Pick on the house
• Win or lose, you walk away ahead. One dollar. No catch.

Spend $10 Get 200 in Bonus Picks

Show Bonus Code

Claim Bonus

Signup Promo Recommended Onyx Odds Bonus

Can be redeemed Yes

T&Cs apply, 18+

$200 in No Sweat Entries + A Free Pick

Show Bonus Code

Claim Bonus

Signup Promo Hot Offer

Min. Purchase $10

Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)

Playthrough 1x Bonus

Can be redeemed Yes

T&Cs apply, 18+

Get 100% on any coins purchase up to $100

Show Bonus Code

Claim Bonus

Signup Promo Hot Offer Thrillzz Bonus

Can be redeemed Yes

T&Cs apply, 18+

N. Arizona vs Arizona Picks, Prediction, Odds, and Line Movement for Saturday September 5 2026

Northern Arizona heads to Tucson on Saturday night to face Arizona at Casino Del Sol Stadium in a matchup that pits a scrappy Lumberjacks team...

Lamar vs Louisiana Picks, Prediction, Odds, and Line Movement for Saturday September 5 2026

Louisiana opens its 2026 season Saturday night at Our Lady of Lourdes Stadium against a Lamar team that already has a quality victory under its...

FAU vs Florida Picks, Prediction, Odds, and Line Movement for Saturday September 5 2026

Hey Florida Atlantic, can we turn the chaos meter down a little bit? From a viewing and entertainment standpoint, Owl games have become must-see TV,...

W. Michigan vs Michigan Picks, Prediction, Odds, and Line Movement for Saturday September 5 2026

The Ann Arbor Police Department would not appreciate this, but no one would fault a Wolverine fan for bringing a shovel to The Big House...

Hull City vs Aston Villa Picks, Prediction, Odds, and Line Movement for Saturday September 5 2026

Hull City hosts Aston Villa at the MKM Stadium on Saturday afternoon in a Premier League matchup where the betting market is still giving Villa...

Nottingham Forest vs Tottenham Picks, Prediction, Odds, and Line Movement for Saturday September 5 2026

Nottingham Forest hosts Tottenham Hotspur at the City Ground on Saturday in a Premier League matchup between two clubs still searching for their first league...

Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions

Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview

Mariners vs Angels Best Free Picks:

• Seattle Mariners -1.5 runs
• OVER 7.5