Los Angeles Dodgers vs Arizona Diamondbacks Pick and Prediction for Thursday September 25, 2025

By: Cameron Ross Published 09/25/2025, 12:15 AM ET

Dodgers vs Diamondbacks Game Information

The Los Angeles Dodgers stayed on the road Thursday night for game three of three in Arizona against the Arizona Diamondbacks at Chase Field at 3:40 PM. Los Angeles is a playoff team with 88 wins on the year, looking to sew up the division title in the final week of the season. Arizona comes into this matchup 3 games above .500 in pursuit of a playoff spot, riding a lengthy winning streak. Stay in the action with our free MLB Picks.

Dodgers Preview

Offensively, Los Angeles has been top tier this season with nearly 800 runs on 1341 hits. The Los Angeles power has carried the team with a .440 team slugging percentage and 234 total home runs. The Los Angeles pitching has been mediocre this season, with a 4.03 team ERA. Freddie Freeman is at the top of the batting order in the Los Angeles offense with a .292 batting average. Shohei Ohtani is the power for Los Angeles, leading the team with 53 home runs and 99 RBIs on the year.

Diamondbacks Preview

The Arizona pitching has been mediocre this season, with a 4.43 team ERA, but the team has allowed only nine total runs over its last three victories. The Arizona offense has been stout this season, boasting a .252 batting average, as the Diamondbacks have scored 778 runs on 1339 total hits. Geraldo Perdomo has done a ton for Arizona this season, leading the team with a .291 batting average and 98 total RBI's.

Dodgers vs Diamondbacks Pitching Matchup

Yoshinobu Yamamoto will take the mound Thursday for Los Angeles with eleven wins and eight losses on the year, 2.58 ERA across 167.2 innings of work. Zac Gallen will counter for Arizona with 13 wins and 14 losses and a 4.70 ERA in just under 188 total innings of work.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Dodgers vs Diamondbacks Pick

Both teams have a ton to play for, but the Dodgers are in the better spot in this game. LA is trying to sew up the division, while the Diamondbacks are trying to get into October. Look for the Dodgers to back their pitcher Thursday night on the road, leading to the win as they inch closer to a division title.

Pick: Los Angeles Dodgers -154

Secondary: Β Over 8.5

Lean: Shohei Ohtani Over 1.5 Bases

Final Score Prediction:Β  Los Angeles Dodgers win 6-4

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+