Milwaukee Brewers vs St. Louis Cardinals Picks and Prediction for Monday May 4 2026

By: Kim Smith Published 05/04/2026, 12:10 AM ET

The Milwaukee Brewers and St. Louis Cardinals meet at Busch Stadium in St. Louis, Missouri, on Monday, May 4, 2026, at 7:45 PM ET, with coverage on MLB.TV/FS1. At the time of this writing the odds were not released. This divisional matchup features two teams with winning records and recent strong performances, and readers can also check out free MLB picks.

Brewers vs Cardinals Starting Pitchers

Milwaukee is expected to start Brandon Sproat, who comes in with an 0-2 record, a 6.75 ERA, a 1.61 WHIP, 26.2 innings pitched, 28 hits allowed, 25 strikeouts, 15 walks, and seven home runs allowed. St. Louis is expected to counter with Kyle Leahy, who enters with a 3-3 record, a 5.52 ERA, a 1.67 WHIP, 29.1 innings pitched, 38 hits allowed, 22 strikeouts, 11 walks, and six home runs allowed.

Milwaukee Riding Momentum Into Division Clash

The Brewers enter this game with an 18-14 overall record and an 8-6 mark on the road. Milwaukee has been playing well recently, having recently won over Washington by scores of 4-1 and 6-1, and also recently winning over Arizona by scores of 13-1 and 13-2. The Brewers recently lost to Arizona 6-2, giving them four wins in their last five games provided.

Milwaukee is batting .242 as a team with 170 runs, 260 hits, 22 home runs, a .338 on-base percentage, and a .359 slugging percentage. On the pitching side, the Brewers have a 3.56 ERA, a 1.26 WHIP, 117 walks, 300 strikeouts, and a .231 opponent batting average. Milwaukee also has a 10-4 day record in the provided team stats.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

The biggest strength for Milwaukee is its pitching efficiency. The Brewers have the lower ERA, lower WHIP, more strikeouts, and lower opponent batting average compared to St. Louis. Even though Milwaukee has fewer home runs, the ability to limit opposing hitters and control innings has been a key factor in its success so far.

St. Louis Building Confidence at Home

The Cardinals come into Monday with a 20-13 overall record and a 9-8 home record. St. Louis has been on an impressive run, recently winning over Los Angeles by scores of 3-2 and 7-2, and also recently winning over Pittsburgh by scores of 10-5, 5-4, and 11-7. That gives the Cardinals five straight wins in the last five games provided.

St. Louis is batting .242 with 165 runs, 268 hits, 44 home runs, a .327 on-base percentage, and a .408 slugging percentage. The Cardinals’ pitching staff has a 4.59 ERA, a 1.42 WHIP, 126 walks, 231 strikeouts, and a .260 opponent batting average. St. Louis also has a 7-7 day record in the supplied team stats.

The key strength for St. Louis is power, as the Cardinals have 44 home runs compared to Milwaukee’s 22. The offensive ability to generate extra-base hits and drive runs gives St. Louis a different profile, though the pitching numbers show higher ERA and WHIP compared to Milwaukee.

Milwaukee Brewers vs St. Louis Cardinals Picks and Prediction

Milwaukee Brewers vs St. Louis Cardinals Pick

  • Pick: Milwaukee Brewers Moneyline

Milwaukee is the pick because the Brewers hold the advantage in overall pitching metrics and recent performance. The Brewers have won four of their last five games provided and carry the lower ERA, lower WHIP, more strikeouts, and lower opponent batting average. While St. Louis has won five straight and has more home run power, the overall pitching edge for Milwaukee stands out in the provided data.

Milwaukee Brewers vs St. Louis Cardinals Total Pick

  • Pick: Take the over if the total is set at 8.5.

I would lean Over 8.5 if that number is available. Both starting pitchers come into this game with ERAs above 5.00, and both teams have shown the ability to score runs recently. Milwaukee has scored 13 runs twice in the last five games provided, while St. Louis has scored 10 and 11 runs in recent wins. With both offenses showing production and both starting pitchers carrying higher ERAs, the data supports a higher-scoring game.

Final Score Prediction: Milwaukee Brewers 6 – St. Louis Cardinals 5

This prediction was written before the completion of game play on Sunday.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+