Minnesota Twins vs Chicago White Sox Picks and Prediction for Thursday May 28 2026

By: Eddie Kline Published 05/28/2026, 12:30 AM ET

Twins Preview

AL Central Division foes will square off on Thursday afternoon, when the Minnesota Twins and the Chicago White Sox wrap up their series from Rate Field. Be ready for the baseball season with all of our MLB predictions. The Twins (27-29) have won seven of their last 11 games and are 5.5 games out of first place. Last night, Minnesota OF Byron Buxton led off the game with his 17th home run of the year during a 15-2 road loss.

Twenty-five year old righty Taj Bradley (5-1 2.77 ERA) is flourishing in his first season with the Twins. Last time out, Bradley (5 IP) allowed one run and retired seven batters by strikes during a 4-2 road victory against Boston.

White Sox Preview

The Chicago White Sox have won 16 of their first 27 home games and trail division leading Cleveland by 3.5 games. During Thursday’s home victory, Chicago 2B Chase Meidroth crushed a grand slam and DH Munetaka Murakami added his 20th home run of the year. SP David Sandlin (1-0) allowed one run across six solid frames to earn his first major league win for the White Sox (28-27).

Twenty-nine year old righty Davis Martin (7-1 2.04 ERA) is making a strong case for his first All-Star Game appearance. Through 61 plus innings, Martin has struck out 66 batters and ranks 12th in the majors with a 1.02 WHIP.

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Twins vs White Sox Pick

Minnesota C Ryan Jeffers had surgery on his fractured left hamate bone and will miss the next 6-to-8 weeks. Through 56 games, Minnesota ranks 12th in OPS and 8th in runs scored. For the season, Chicago ranks 11th in OPS and 14th in runs scored. Take the White Sox to win at home. Final Score Prediction, Chicago White Sox win 5-2.