Minnesota Twins vs Los Angeles Angels Picks and Predictions for Monday, September 8, 2025

By: David Anicetti Published 09/08/2025, 12:05 AM ET

The Minnesota Twins visit the Los Angeles Angels at Angel Stadium on Monday night, with the first pitch at 9:38 PM ET. Minnesota enters at 62-80 with a 27-44 road mark, while Los Angeles is 66-76 and 34-37 at home. Bettors looking for an advantage can tap into our free MLB picks as these clubs try to snap recent skids.

Minnesota Twins Preview

The Twins’ lineup has leaned on Byron Buxton, who leads the team at .270 with 29 homers and 73 RBIs. Minnesota’s team slash line is .239/.311/.396 with 165 homers, and recent results have been poor with five straight losses. If Ryan Jeffers (team-best .353 on-base percentage) is back from his day-to-day status, that boosts on-base ability for a club needing baserunners ahead of Buxton.

Simeon Woods Richardson gets the ball for Minnesota at 5-4 with a 4.53 ERA and 1.40 WHIP over 89.1 innings. The right-hander has allowed 85 hits and 40 walks with 78 strikeouts. The Twins’ staff overall sits at a 4.58 ERA and 1.33 WHIP, with opponents hitting .259, which means the Twins will have to be strong at the plate.

Los Angeles Angels Preview

At the plate, the Angels have produced more than Minnesota, with 197 homers to Minnesota’s 165. Jo Adell leads with 34 homers and is second with 92 RBIs, while Taylor Ward leads with 95 RBIs despite a .227 average, and Zach Neto has 25 homers with 125 hits. Mike Trout’s .362 on-base percentage is the team’s best.

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Los Angeles has not named a starter for Monday. The Angels’ pitching numbers are similar to Minnesota’s, with a 4.82 ERA and 1.44 WHIP, and opponents are batting .261. Los Angeles may start a pitcher from the bullpen and then follow with relievers throughout, as they have done of late.

Twins vs Angels Prediction

The Angels’ power and slightly better overall stats both at the plate and on the mound favor Los Angeles playing at home. With both staffs having ERAs higher than 4.50, run scoring should be high and that means take the over in this matchup. Final Score Prediction: Los Angeles Angels win 7-4.