New York Mets vs Washington Nationals Picks and Prediction for Thursday May 21 2026

By: Eddie Kline Published 05/21/2026, 12:30 AM ET

Mets Preview

In Thursday afternoon MLB action, the New York Mets and the Washington Nationals will wrap up their series from the nationโ€™s capital. Be ready for the baseball season with all of our MLB predictions. The Mets (21-28) have dropped 15 of their first 25 road games and are trapped in the NL East Division basement. Last night, New York OF Juan Soto homered twice and drove in three runs during an 8-4 road loss.

New York manager Carlos Mendoza has not announced a starting pitcher for this contest. The Mets currently ranks tenth in the majors with a 3.82 ERA and a respectable 1.29 WHIP. New York starters have notched 13 quality starts.

Nationals Preview

The Washington Nationals are five games below. 500 at home and are nine games behind Atlanta for first place in the NL East Division. During Wednesdayโ€™s home victory, Washington jumped out to a first inning lead on a C.J. Abramsโ€™ three-run shot. SP Zack Littell (3-4) gave up three runs across five frames to earn the win for the Nationals, who evened their record at 25-25 overall.

Twenty-seven year old righty Cade Cavalli (2-2 4.05 ERA) will make his 11th start of the year for the Nationals. Last time out, Cavalli (6.1 IP) allowed three runs and retired eight batters by strikes during a 13-3 home victory versus Baltimore.

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Mets vs Nationals Pick

New York SS Francisco Lindor is recovering from a calf injury and is not expected to return to the lineup until next month. Through 49 games, New York ranks 30th in OPS and 23rd in runs scored. For the season, Washington ranks 5th in OPS and 1st in runs scored. Take the Nationals to win at home. Final Score Prediction, Washington Nationals win 5-3.

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