New York Yankees vs Cleveland Guardians Picks and Prediction for Wednesday June 10 2026

By: Eddie Kline Published 06/10/2026, 12:10 AM ET

Yankees Preview

In Wednesday afternoon MLB action, the New York Yankees and the Cleveland Guardians will wrap up their series from Progressive Field. Be ready for the baseball season with all of our MLB predictions. The Yankees (40-26) have won seven of their last 11 games and are locked in a tie with Tampa Bay for first place in the AL East Division. Last night, 2B Jazz Chisholm Jr. broke an eighth inning tie with a solo shot to lift New York to a 3-2 road victory.

Thirty-three year old southpaw Carlos Rodon (1-2 2.88 ERA) will make his sixth start of the year for the Yankees. Last time out, Rodon (6 IP) allowed one run and fanned seven batters during a 2-1 home victory versus Cleveland.

Guardians Preview

The Cleveland Guardians have dropped seven of their previous 11 games and hold a one-game lead over Chicago for the top spot in the AL Central Division. During Tuesday’s home loss, Cleveland batters went 2-for-10 with runners in scoring position and left 13 men on base. All-Star 3B Jose Ramirez went 2-for-5 and scored a run for the Guardians (37-32), who fell to 17-16 at home.

The Guardians will counter with twenty-five year old southpaw Parker Messick (6-2 2.40 ERA) on Wednesday. Through 75 innings of work, Messick has retired 78 batters by strikes and owns a sparkling 1.07 WHIP.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Yankees vs Guardians Pick

New York OF Aaron Judge suffered a stress fracture of his right first rib and will miss the next four-to-six weeks. Through 66 games, New York ranks 2nd in OPS and 6th in runs scored. For the season, Cleveland ranks 26th in OPS and 19th in runs scored. Take the Guardians to win at home. Final Score Prediction, Cleveland Guardians win 4-3.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+