New York Yankees vs Minnesota Twins Picks and Predictions for Wednesday, September 17, 2025

By: Cameron Ross Published 09/17/2025, 12:50 AM ET

Yankees vs Twins Game Information

The New York Yankees stay on the road Wednesday night with another game in Minnesota against the Minnesota Twins at 7:40 PM in Target Field. New York is fighting for a playoff spot, coming into this game, currently five games back of Toronto in the American League East. Minnesota, on the other hand, is one of the worst teams in the American League, 19 games back in the American League Central, having already been eliminated from playoff contention. Stay in the action with our MLB picks.

Yankees Preview

Aaron Judge is the offensive leader this season for New York, leading the team with a .325 batting average, 48 home runs, and 102 RBIs. As a team, New York has hit the ball well all season, with a .248 batting average. The Yankees have scored 774 runs on 1259 hits. The Yankees’ pitching has struggled at times with a 4.02 ERA.

Twins Preview

Byron Buxton does everything for the Minnesota office this season, leading the team with a .271 batting average, 31 home runs, and 76 RBI's. Minnesota has been a bottom-feeder in the league this year, with a .240 batting average, having scored 639 runs and 1208 hits. The Minnesota pitching has been one of the worst in the MLB with a 4.58 ERA as a team.

Yankees vs Twins Pitching Matchup

Luis Gil will take the mound for New York Wednesday night with a 4-1 record and a 2.83 ERA across 41.1 innings of work. Taj Bradley will counter for Minnesota on Wednesday night. Bradley has six wins and seven losses this season and a 4.88 ERA in just under 133 innings.

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Yankees vs Twins Pick

Minnesota has nothing left to play for entering the final weeks of the season and will likely struggle in this game. New York, on the other hand, must continue to win if they are to secure a playoff spot. Take New York on Wednesday night to do the job as they get the win on the road in Minnesota to conclude their series with the Twins.

Pick: New York YankeesΒ 

Secondary: Over

Lean: Aaron Judge RBI

Final Score Prediction: New York Yankees win 7-4

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