Philadelphia Phillies vs. Arizona Diamondbacks Picks and Predictions for Saturday September 20, 2025

By: Dylan Hellebrand Published 09/20/2025, 12:40 AM ET
Cardinals vs Phillies prediction

On Saturday, the Philadelphia Phillies (91-62) face off against the Arizona Diamondbacks (77-76) at Chase Field in Phoenix, Arizona. The game will be aired on NBC Sports Philadelphia and DBACKS.TV. Keep up to date with all the MLB action, with our MLB picks.

Game Information For Phillies vs Diamondbacks

  • September 20, 2025, 8:10pm EST
  • Chase Field
  • NBC Sports Philadelphia/DBACKS.TV
  • 99° sunny at start time

Arizona Diamondbacks Form & Recent Results

Arizona enters this game following a single loss, but they've been playing well overall, winning four out of their last five games before facing Philadelphia on Friday. Their most recent defeat came in an 11-inning, 5-1 loss to San Francisco on Wednesday. In that contest, starting pitcher Brandon Pfaadt delivered an outstanding performance for the Diamondbacks, throwing nine innings of nearly flawless baseball as he surrendered only one hit, didn’t allow an earned run, walked just one batter, and struck out seven. On offense, Corbin Carroll has been the Diamondbacks’ most prolific power hitter this season, leading the team with 30 home runs. Ketel Marte has also been a key source of offense, currently ranking second on the team with 25 homers. Geraldo Perdomo has been Arizona’s top run producer, pacing the squad with 97 RBIs so far. Perdomo is also getting it done at the plate with consistency, as he leads the team with a .289 batting average. In their last five games, the Diamondbacks have averaged 5.2 runs as they continue to compete closely with three other teams for the final NL Wild Card spot. Altogether, Arizona averages an even 5 runs per game on the season, showcasing a strong and steady offense as the postseason race heats up.

Philadelphia Phillies Form & Recent Results

The Phillies head into this matchup having dropped their last game, but they have still managed to win three of their previous five games leading up to Friday's clash with Arizona. In their most recent game on Wednesday, the Phillies were shut out 5-0 by the Dodgers. Philadelphia starter Jesus Luzardo went seven innings in that game, surrendering six hits and four earned runs, with one walk and six strikeouts. When it comes to offensive power, Kyle Schwarber has been the main force for the Phillies this year, belting a team-high 53 home runs. Bryce Harper has also contributed significantly with 27 homers, making him Philadelphia’s second-highest home run hitter for the season. Schwarber isn't just leading in home runs; he also tops the team in RBIs, driving in 128 runs so far. Trea Turner has been Philadelphia’s most consistent hitter at the plate, boasting a .305 batting average for the season—the best on the team. Over their last five games, the Phillies’ offense has averaged 5.2 runs per contest, indicating that their lineup remains potent as they look to derail the Diamondbacks’ postseason aspirations. Having already secured the NL East division title, the Phillies are shifting their focus to preparations for the upcoming playoffs. Over the course of the season, Philadelphia has averaged 4.9 runs per game, demonstrating steady offensive production as they approach the postseason.

Starting Pitchers For Phillies and Diamondbacks

  • Philadelphia’s Aaron Nola on the road this year: 0-5, 7.00 ERA, 42 K
  • Arizona’s Zac Gallen at home this season: 5-7, 4.61 ERA, 85 K

Phillies vs Diamondbacks Picks and Prediction

The Phillies have already locked in their place in the postseason, giving them some breathing room as the regular season winds down. In contrast, the Diamondbacks are in a fierce fight to keep their playoff hopes alive, competing against three other teams for the last wild card spot. Every game counts for Arizona, and they'll face a challenge against Philadelphia, even though Phillies pitcher Aaron Nola has struggled mightily away from home, failing to earn a single road win this year. Nola’s overall record stands at 4-9 with an elevated 6.44 ERA. Meanwhile, the Diamondbacks will turn to Zac Gallen on the mound. Gallen has had an up-and-down season himself, posting a 12-14 win-loss record with a 4.73 ERA, hoping he can deliver a strong performance when his team needs it most. Final Score Prediction, Arizona Diamondbacks win 5-4.

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