San Francisco Giants vs Los Angeles Dodgers Picks and Prediction for Thursday September 18 2025

By: Cameron Ross Published 09/18/2025, 12:20 AM ET

Giants vs Dodgers Game Information

The San Francisco Giants will begin a 4-game road trip Thursday with a game in Los Angeles against the Los Angeles Dodgers at 10:10 PM inside Dodger Stadium. San Francisco has 76 wins and 76 losses this season, following a four-run victory in the 11th inning against the Arizona Diamondbacks on Wednesday to end a lengthy losing streak. The Los Angeles Dodgers stay home on Thursday with 84 wins, currently the top team in the National League West, riding a 2-game skid. Stay in the action with our MLB Picks.

Giants Preview

Jung Hoo Lee leads the San Francisco offense this season with a .262 batting average. Willy Adames has been vital for San Francisco, leading the team with 28 home runs and 82 RBIs this season. Offensively, San Francisco has been a bottom-feeder in the league, with a .237 batting average. The Giants have scored only 657 runs on 1187 hits. The San Francisco bullpen has been top tier this year with a 3.87 team ERA.

Dodgers Preview

Freddie Freeman is the best bat in the Los Angeles lineup this year with a .294 batting average. Shohei Ohtani leads the team with fifty home runs and 94 RBIs on the year. Offensively, Los Angeles is one of the best teams in the league with a .254 batting average. The Dodgers have scored 773 runs or 1301 hits this season.

Giants vs Dodgers Pitching Matchup

Logan Webb will be on the mound Thursday for San Francisco. This season, Webb has fourteen wins and 10 losses and a 3.34 ERA across 188.2 innings of work. Yoshinobu Yamamoto We'll take the mound for Los Angeles with eleven wins and eight losses and a 2.66 ERA in just over 162 innings.

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Giants vs Dodgers Pick

The Los Angeles Dodgers are in a better spot in this game as they are currently fighting for the top spot in their division. Look for Los Angeles to do the work on both sides of the dish as they overwhelm San Francisco for 9 innings. Take the Dodgers on Thursday night at home to get the win in Game 1 of this series.

Pick: Los Angeles Dodgers -155

Secondary: Over 8

Lean: Shohei Ohtani Over .5 RBIs

Final Score Prediction: Los Angeles Dodgers win 8-3.

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