San Francisco Giants vs. Los Angeles Dodgers Picks and Predictions for Saturday September 20, 2025

By: Dylan Hellebrand Published 09/20/2025, 12:45 AM ET
Pirates vs Dodgers picks

On Saturday, the San Francisco Giants (76-77) face off against the Los Angeles Dodgers (86-67) at Dodger Stadium in Los Angeles, California. The game will be aired on NBC Sports Bay Area and Sportsnet Los Angeles. Keep up to date with all the MLB action, with our MLB picks.

Game Information For Giants vs Dodgers

  • September 20, 2025, 9:10pm EST
  • Dodger Stadium
  • NBC Sports Bay Area/Sportsnet Los Angeles
  • 78° sunny at start time

Los Angeles Dodgers Form & Recent Results

Los Angeles enters this matchup riding a two-game winning streak, having won three of their last five games before facing San Francisco again on Friday. In Thursday’s 2-1 victory over the Giants, Dodgers pitcher Yoshinobu Yamamoto delivered an impressive performance, throwing 5.1 innings in which he allowed just one hit and no earned runs. Although Yamamoto issued six walks, he was able to strike out seven San Francisco batters, helping to keep their offense in check. This season, Shohei Ohtani has been the Dodgers’ main power source, leading the team with an impressive 51 home runs. Andy Pages ranks second on the team in home runs, having hit 25 so far this year. Ohtani also tops the Dodgers’ RBI chart, driving in 95 runs to lead the team in that category. Freddie Freeman has been the club’s most consistent hitter, boasting a team-high batting average of .295. Offensively, the Dodgers have been hot, averaging 5.6 runs per game over their last five games as their bats have come alive recently. Over the course of the season, Los Angeles is producing an average of 5.1 runs per game, showcasing the strength and consistency of their lineup.

San Francisco Giants Form & Recent Results

San Francisco heads into this matchup riding a one-game losing streak, having dropped four of their last five games leading up to Friday's contest against the Dodgers. In their most recent game, a tight 2-1 defeat to the Dodgers on Thursday, starting pitcher Logan Webb delivered a solid performance for the Giants. Webb threw seven innings, giving up just four hits and one earned run, while walking one batter and striking out five. At the plate, Willy Adames has been the primary power hitter for San Francisco this season, leading the team with 28 home runs. Matt Chapman has also made a significant impact, ranking second on the team with 21 homers. Adames not only leads in home runs but is also the Giants' top run producer, topping the squad with 82 RBIs so far this year. When it comes to batting average, Jung Hoo Lee stands out, boasting a team-leading average of .261 for the season. Recently, the Giants have struggled on the mound, allowing an average of 5.4 runs per game over their last five games. As the fight for the final wild card spot remains close, every game is crucial for San Francisco, and they can’t afford to let their skid continue. Throughout the season, the Giants have managed to score an average of 4.3 runs per game, highlighting a need for both improved offense and pitching as the playoff race heats up.

Starting Pitchers For Giants and Dodgers

  • San Francisco’s Kai-Wei Teng on the road this year: 1-3, 5.85 ERA, 29 K
  • Los Angeles’ Tyler Glasnow at home this season: 2-2, 2.38 ERA, 73 K

Giants vs Dodgers Picks and Prediction

The Giants are in a heated race for the last NL wild card spot, going head-to-head with the Mets, Reds, and Diamondbacks as the regular season winds down. Every game matters for San Francisco, and their latest challenge is a tough road series against the formidable Los Angeles Dodgers. The Dodgers, on the other hand, are locked in a battle of their own as they try to hold off the Padres for first place in the NL West division. On the mound for the Giants will be Kai-Wei Teng, who has struggled so far this season with a 2-4 record and a high 6.41 ERA. The Dodgers will counter with Tyler Glasnow, who has been much more effective, posting a 3-3 record and a solid 3.06 ERA. Final Score Prediction, Los Angeles Dodgers win 2-1.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+