San Francisco Giants vs Pittsburgh Pirates Picks and Prediction for Tuesday September 1 2026

By: Eddie Kline Published 09/01/2026, 12:05 AM ET

Giants Preview

In Tuesday night MLB action, the San Francisco Giants will invade PNC Park to take on the Pittsburgh Pirates. Be ready for the baseball season with all of our MLB predictions. The Giants (57-81) have dropped 45 of their first 69 road games and own the second worst overall record in the National League. Last night, Turner Hill delivered a pinch-hit two-run double in the sixth inning to propel San Francisco to a 7-3 road victory against Atlanta. DH Rafael Devers contributed his 30th home run and scored twice. 

Twenty-nine year old righty Logan Webb (8-8 3.72 ERA) has been one of the few bright spots for the Giants this year. Through 147 plus innings, Webb has limited opponents to just 11 home runs and ranks 15th in the majors with a 1.10 WHIP. 

Pirates Preview

The Pittsburgh Pirates have split their previous ten games and are six games back in the race for the final National League Wild Card spot. On Sunday, Pittsburgh OF Esmerlyn Valdez started the scoring with a two-run blast and SS Jared Triolo added a solo shot during a 5-4 road victory against St. Louis. SP Braxton Ashcraft (14-5) allowed two runs in five innings to earn the win for the Pirates, who improved to 67-71 on the year. 

The Pirates will counter with reigning National League Cy Young Award winner Paul Skenes (9-11 3.79 ERA) in the series opener. Through 145 innings of work, Skenes ranks ninth in the majors with 175 strikeouts and owns a sparkling 1.12 WHIP.

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Giants vs Pirates Pick

Pittsburgh SS Konnor Griffin (finger) is currently on a rehab assignment with Double-A Altoona and should rejoin the lineup this week. Through 138 games, San Francisco ranks 22nd in OPS and 25th in runs scored. For the season, Pittsburgh ranks 7th in OPS and 5th in runs scored. Take the under. Final Score Prediction, Pittsburgh Pirates win 3-2. 

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