Seattle Mariners at Detroit Tigers Picks and Predictions for Wednesday, October 8, 2025

By: David Anicetti Published 10/08/2025, 12:00 AM ET

The Seattle Mariners visit the Detroit Tigers at Comerica Park on Wednesday, October 8, at 3:08 PM ET on FS1 for Game 4 of the American League Division Series. Seattle leads the series 2–1 after Tuesday’s 8–4 win, powered by three home runs. Detroit is a -120 favorite, with the total set at 8.5 runs. The Mariners can advance to the ALCS with another victory. Clinch the series with our free MLB picks.

Seattle Mariners Preview

Seattle’s lineup broke out in Game 3, scoring eight runs on eight hits to take a commanding lead in the series. Cal Raleigh continued his postseason surge with a two-run homer and three RBI, while J.P. Crawford added two hits and a solo shot. Eugenio Suárez’s early blast set the tone as the Mariners hit three homers overall.

Seattle’s pitching remains steady with a 3.87 ERA and 1.22 WHIP for the season. Logan Gilbert went six strong innings on Tuesday with seven strikeouts and no walks before handing it to a rested bullpen. Andrés Muñoz and Matt Brash each recorded scoreless innings. Seattle has not announced a Game 4 starter, but its bullpen is positioned well after limited use the past two days.

Detroit Tigers Preview

Detroit’s offense has gone cold at the wrong time, scoring just seven total runs over the last two games. Spencer Torkelson and Riley Greene must spark the lineup early to avoid another deficit. The Tigers hit .247 this season with 198 home runs and a .316 on-base percentage, but have struggled to produce consistent contact in the series.

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Right-hander Casey Mize gets the start after throwing three innings of one-run ball in his last outing in the wild-card series. Detroit’s bullpen was heavily used Tuesday, with five relievers combining for five and two-thirds innings. Manager A.J. Hinch needs Mize to pitch into at least the sixth or seventh, to keep bullpen arms fresh if the series goes the distance.

Seattle Mariners at Detroit Tigers Prediction

Seattle’s bats have come alive, and the bullpen has handled late innings with confidence. Detroit’s pitching staff is tired, and unless Mize delivers deep into the game, Seattle’s lineup will continue to bound the ball around Comerica Park. Final Score Prediction: Seattle Mariners win 6-3.