Seattle Mariners vs Kansas City Royals Picks and Prediction for Thursday September 18 2025

By: Cameron Ross Published 09/18/2025, 12:00 AM ET

Mariners vs Royals Game Information

The Seattle Mariners continue their road trip Thursday afternoon with another game in Kauffman Stadium against the Kansas City Royals at 2:10 PM. Seattle is currently the top team in the American League West with 83 wins this season. The Kansas City Royals stay at home on Thursday, one game below .500, 10 games back in the American League Central. Stay up to date with our MLB Picks.

Mariners Preview

Offensively, Seattle was the better team in their last outing, scoring 12 runs on 14 total hits. Cal Raleigh led the way for the Seattle offense last game with three hits in five at-bats, including two home runs to drive in three total runs. Julio Rodriguez chipped in heavily as well with two hits and four at-bats to drive in two runs in the game. Dominic Canzone erupted in the last game with five hits and five at-bats, including three home runs, to drive in four of the 12 Seattle runs.

Royals Preview

Michael Wacha got the start and took the loss for Kansas City in their last outing, giving up seven runs on nine hits across only 2.2 innings of work. The Kansas City bullpen was terrible as well, giving up five more runs on five hits over the final 6.1 innings of the game. Carter Jensen led the way for the Kansas City offense in their last game with three hits and four at-bats to drive in three runs.

Mariners vs Royals Pitching Matchup

Luis Castillo will take the mound Thursday for Seattle. Castillo has nine wins and eight losses, accompanied by a 3.76 ERA across 167.1 innings of action. Stephen Kolek will get the ball for Kansas City on Thursday, with five wins and five losses and a 3.71 ERA in just under 100 innings.

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Mariners vs Royals Pick

The Seattle Mariners have a ton more to play for in this matchup, and it will show on Thursday. Look for the Mariners to do the work on both sides of the dish to overwhelm a mediocre Kansas City team. Take Seattle on Thursday afternoon on the road to get the win in Kansas City as they continue to push towards the playoffs.

Pick: Seattle MarinersΒ 

Secondary: OverΒ 

Lean: Julio Rodriguez RBI

Final Score Prediction: Seattle Mariners win 8-4

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