St. Louis Cardinals vs Pittsburgh Pirates Picks and Prediction for Monday April 27 2026
Cardinals Preview
NL Central Division rivals will square off on Monday night, when the St. Louis Cardinals travel to PNC Park to take on the Pittsburgh Pirates. Be ready for the baseball season with all of our MLB predictions. The Cardinals (14-13) are looking to snap a four-game losing streak and are tied with Milwaukee for last place. On Sunday, St. Louis OF Nathan Church and 2B J.J. Wetherholt each homered during a 3-2 home loss versus Seattle.
Twenty-eight year old righty Dustin May (3-2 5.84 ERA) is attempting to resurrect his career after a disappointing season in Boston. The Cardinals have won May’s last three starts and he has allowed just four runs over his last 17 plus innings.
Pirates Preview
The Pittsburgh Pirates are three games above .500 at home and are two games behind first place Cincinnati. On Sunday, Pittsburgh batters managed just two hits and left six men on base during a 5-0 road loss against Milwaukee. SP Carmen Mlodzinski (1-2) gave up four runs in three plus innings and took the loss for the Pirates.
Twenty-six year old righty Braxton Aschcraft (1-1 2.43 ERA) will come off the bereavement list to start for the Pirates. Last time out, Ashcraft (7 IP) gave up four hits and two runs during an 8-4 road victory against Texas.
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Cardinals vs Pirates Pick
Pittsburgh SS Jared Triolo (knee) will begin a rehab assignment with Single-A Bradenton this week. Through 27 games, St. Louis ranks 14th in OPS and 13th in runs scored. For the season, Pittsburgh ranks 15th in OPS and 7th in runs scored. Take the Pirates to win at home. Final Score Prediction, Pittsburgh Pirates win 5-3.
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