Tampa Bay Rays vs Chicago Cubs Picks and Prediction for Saturday September 13 2025

By: Eddie Kline Published 09/13/2025, 12:45 AM ET

Rays Preview

The Saturday MLB schedule will get underway with a matinee between the Tampa Bay Rays and the Chicago Cubs from Wrigley Field. Be ready for the baseball season with all of our MLB predictions. The Rays (72-75) have lost three straight games and are on the verge of being eliminated from postseason contention. In the series opener, Tampa Bay Christopher Morel’s three-run blast in the opening frame was not enough offense during a 6-4 road loss.

Thirty year old righty Drew Rasmussen (10-5 2.64 ERA) has quietly put together a stellar season for the Rays. Through 139 plus innings, Rasmussen has issued just 31 walks and owns a sparkling 0.98 WHIP.

Cubs Preview

The Chicago Cubs have won 45 of their 73 home games and are sitting comfortably atop the NL Wild Card standings. During Friday’s home victory, Chicago OF Ian Happ fell a triple short of the cycle and drove in a pair of runs. 2B Nico Hoerner contributed two hits and scored twice for the Cubs (84-63), who trail NL Central Division leading Milwaukee by five games.

Chicago skipper Craig Counsell will give the nod to righty Colin Rea (10-6 4.20 ERA) on Saturday. In his last start, Rea (5.1 IP) allowed one run and retired six batters by strikes during a 6-3 home loss versus Washington.

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Rays vs Cubs Pick

Chicago OF Kyle Tucker has been placed on the 10-day injured list with a left calf strain and will not play in this series. Through 147 games, Tampa Bay ranks 13th in OPS and 14th in runs scored. For the season, Chicago ranks 9th in OPS and 8th in runs scored. Take the Rays to win on the road. Final Score Prediction, Tampa Bay Rays win 5-3.

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