Texas Rangers vs Houston Astros Picks and Predictions for Monday, September 15, 2025

By: David Anicetti Published 09/15/2025, 12:10 AM ET

The Texas Rangers and Houston Astros square off Monday night at Daikin Park in Houston, with the first pitch set for 8:10 PM ET on MLB.TV. Texas comes in at 79–70 overall and just 32–42 on the road, while Houston stands at 81–68 with a strong 43–32 home record. Win big with our free MLB Picks.

Texas Rangers Preview

Texas is on a roll, winning six straight, including back-to-back road victories against the Mets. The Rangers’ lineup has been short-handed with Adolis García (73 RBI) and Corey Seager (21 home runs) both on the injured list, leaving Wyatt Langford and Josh Smith to lead the offense. As a team, Texas is batting .237 with 164 home runs, relying more on pitching than hitting to win games. Texas trails both the American League West and the final AL wild card spot by two games.

Jack Leiter starts on the mound Monday, with a 9–8 record and 3.81 ERA over 132.1 innings. He has struck out 130 but walked 64, so command will be a key factor against an Astros lineup known for its patience. Texas pitching has been strong all year with a 3.41 ERA and 1.17 WHIP, ranking among the best in the league.

Houston Astros Preview

The Astros have won two straight and have been steady at home all season. Jose Altuve leads the team with 25 home runs and 70 RBI, though his status is listed as day-to-day. Christian Walker has 23 homers and 80 RBI, while Jeremy Peña has been their most consistent hitter with a .299 average and .820 OPS. Houston’s lineup is deeper than Texas’, giving them an advantage, especially if Altuve plays. Texas is tied for first place in the American League West with Seattle.

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Jason Alexander gets the start for Houston. He is 4–1 with a 4.19 ERA in 66.2 innings. While not a high strikeout pitcher (55 Ks), Alexander does not give up big innings, and often works deep into the game, giving the Houston bullpen much-needed rest. The Astros' bullpen has an ERA of 3.83.

Prediction Texas Rangers vs Houston Astros

With the Rangers missing key hitters and starter Jake Leiter’s tendency to walk hitters, Houston’s batters and home field give them the edge. The Astros are the safer play at home with Alexander on the mound. Final Score Prediction: Houston Astros win 6-3.