Toronto Blue Jays vs Boston Red Sox Picks and Prediction for Tuesday June 16 2026

By: Eddie Kline Published 06/16/2026, 12:05 AM ET

Blue Jays Preview

AL East Division foes will battle on Tuesday night, when the Toronto Blue Jays travel to Fenway Park to take on the Boston Red Sox. Be ready for the baseball season with all of our MLB predictions. The Blue Jays (34-38) have dropped 20 of their first 33 road games and are ten games out of first place. On Sunday, Toronto OF Nathan Lukes went 3-for-5 with an RBI and a run scored during an 8-3 home loss versus New York.

Thirty year old right-hander Dylan Cease (3-3 2.91 ERA) will head to the hill for the Blue Jays in this contest. Through 68 innings of work, Cease ranks third in the majors with 103 strikeouts and sports a solid 1,16 WHIP.

Red Sox Preview

The Boston Red Sox have lost a major league worst 22 of their first 34 home games and are trapped in the division basement. On Sunday, 1B Willson Contreras homered twice during a 6-4 home loss versus Texas. SP Connelly Early (5-5) was roughed up for 11 hits and six runs for the Red Sox, who fell to a disappointing 29-40 overall.

Boston interim manager Chad Tracy will give the nod to twenty-three year old lefty Payton Tolle (3-3 2.70 ERA) in the series opener. Last time out, Tolle (6 IP) was tagged for nine hits and four runs during a 4-3 road loss against Tampa Bay.

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Blue Jays vs Red Sox Pick

Toronto 1B Vladimir Guerrero Jr. (back) was not in Sunday’s lineup and is listed as day-to-day. Through 72 games, Toronto ranks 22nd in OPS and 21st in runs scored. For the season, Boston ranks 24th in OPS and 29th in runs scored. Take the Blue Jays to win on the road. Final Score Prediction, Toronto Blue Jays win 4-3.