Toronto Blue Jays vs New York Yankees Picks and Predictions for Friday, September 5, 2025

By: David Anicetti Published 09/05/2025, 12:20 AM ET

Blue Jays vs Yankees Game Information

The Toronto Blue Jays visit the Big Apple on Friday to play the New York Yankees at 7:05 p.m. ET and can be seen on MLBN and YES. Toronto is clinging to a 3.5-game lead in the American League East over both the Yankees and Boston Red Sox. This series is a big test for the Blue Jays early in the final month of the season. The best MLB Picks can be played here.

Blue Jays Preview

Toronto won two out of three in its series versus Cincinnati, which was completed on Wednesday. The Blue Jays scored a combined 25 runs in their two victories over the Reds, but gave up 18 runs in the same two games. Overall, Toronto has won three of its last four.

George Springer has 27 home runs to lead the Blue Jays, and Vladimir Guerrero Jr is second with 22. Bo Bichette has a team-best 91 RBI, and Guerrero Jr is second with 77. Toronto has scored plenty of runs, with five players having 65 or more RBI. The Blue Jays are batting .270, which is first in baseball, and are fourth in slugging percentage at .435.

Yankees Preview

The Yankees have lost two of the last three, but before that, they had won seven straight. New York currently is tied with Boston for the lead in the AL wildcard race. New York is getting it done at the plate as the Yankees are first in slugging percentage at .458 and in runs scored with 733, for an average of 5.31 runs per game.

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Aaron Judge has been New York's biggest contributor at the plate, leading the Yankees in home runs with 43, RBI with 97, hits with 152, and on-base percentage at .440. Trent Grisham has hit 29 home runs, which are second best for the Yankees. The Yankees have four hitters who have knocked in 70 or more runs.

Blue Jays and Yankees Pitching Matchup

Kevin Gausman starts on the mound for Toronto on Friday. The right-hander is 8-10 with a 3.75 ERA, 157 strikeouts, and 1.05 WHIP. Gausman is coming off a strong effort, allowing just one run in seven innings. The right-hander has performed well in four of his last five starts. Cam Schlittler gets the nod on the mound Friday for the Yankees. The right-hander is 2-2 with a 2.61 ERA, 54 strikeouts, and 1.24 WHIP. The 24-year-old has performed well in five consecutive outings, giving up just five runs in 28.2 innings with the Yankees 3-2 over the five games.

Blue Jays vs Yankees Odds

The current odds have New York favored at -115, while Toronto is +105. The over/under total is 8.5.

Blue Jays vs Yankees Pick

Although both pitchers have performed well recently, Toronto and New York have powerful lineups and will push across plenty of runs, making the over a strong play in this matchup. The Yankees on the moneyline is another solid choice with Schlittler performing well on the mound, New York’s lineup scoring an average of 5.31 runs per game, and playing in front of a raucous Big Apple crowd.