Toronto Blue Jays vs Tampa Bay Rays Picks and Predictions for Tuesday, September 16, 2025

By: David Anicetti Published 09/16/2025, 12:30 AM ET

The Toronto Blue Jays head to George M. Steinbrenner Field on Tuesday to play the Tampa Bay Rays at 7:35 p.m. ET, streaming on MLB.TV. Toronto is 87–62 (37–37 away) and Tampa Bay is 73–76 (38–36 home). Toronto beat Baltimore 11-2 on Sunday, while Tampa Bay lost to the Chicago Cubs 4-3. Hit a home run with our MLB Free Picks.

Toronto Blue Jays Preview

Toronto rolls into this series riding a 4–1 stretch after two series wins over Houston and Baltimore, scoring 28 runs across those four victories. The lineup has been steady all season: .270 avg, .338 on-base percentage, .433 slugging percentage with 178 homers. George Springer leads with 29 home runs and 75 RBI, Vladimir Guerrero Jr. has a .397 on-base percentage, and Bo Bichette sits at .311 avg with 94 RBI and 181 hits (currently on the 10-day IL, listed to return Sep. 17).

Jose Berrios starts for Toronto (9–5, 3.99 ERA, 1.29 WHIP, 160 IP, 135 K, 52 BB, 24 HRs allowed). Berrios limits damage when he keeps the ball in the park and works ahead on the count. With the Jays’ bullpen performing well and an offense that reaches base more often than Tampa Bay’s, Toronto has multiple ways to push runs across the plate.

Tampa Bay Rays Preview

Tampa Bay has dropped four of five. This season, the Rays sit at .252/.313/.405 with 171 home runs. Junior Caminero powers the order (44 home runs, 108 RBI), while Yandy Díaz adds contact and base hits (.291 avg, .350 on-base percentage, 160 hits). The Rays are 38–36 at home.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Ryan Pepiot goes for Tampa Bay (11–10, 3.59 ERA, 1.13 WHIP, 163 IP, 161 K, 57 BB, 26 home runs allowed). Pepiot makes hitters swing and miss and can keep the bases empty more than most. Tampa Bay has had problems of late knocking in runs, as they are stranding runners in scoring position more often than earlier this season.

Toronto vs Tampa Bay Prediction

Toronto’s stronger on-base percentage and recent run of scoring give the Jays the edge in a close matchup. Berrios and Pepiot are both capable, but Toronto’s .338 on-base percentage versus Tampa Bay’s .313 points to more baserunners and more chances to push across runs. Final Score Prediction: Toronto Blue Jays win 7-3.