Chicago Bulls vs Detroit Pistons Picks and Prediction for Wednesday November 12 2025

By: Eddie Kline Published 11/12/2025, 12:50 AM ET

Bulls Preview

Little Caesars Arena will play host to a Wednesday night NBA clash between the Chicago Bulls and the Detroit Pistons. For other NBA action see our NBA Predictions. The Bulls (6-4) have dropped three of their first four road games and rank 12th in the league in offensive efficiency. On Monday, Chicago was outscored by 13 points during the fourth quarter of a 121-117 home loss versus San Antonio.

Kevin Huerter led five Chicago players in double figures with 23 points (8-14 FG), five rebounds, and five assists. Tre Jones and Ayo Dosunmu scored 20 points each on a combined 14-for-27 shooting effort. Matas Buzelis added 15 points and five rebounds for the Bulls. The best sportsbooks are the best way to go when you are betting on the Chicago Bulls.

Pistons Preview

The Detroit Pistons have reeled off seven straight victories and are sitting atop the Eastern Conference standings. The Pistons (9-2) rank second in the league in defensive efficiency and are allowing 112.7 points per contest. On Monday, Detroit rallied from as many as 13 points down to earn a 137-135 overtime victory versus Washington.

All-Star G Cade Cunningham poured in a game-high 46 points (14-45 FG) to go along with 12 rebounds and 11 assists. Daniss Jenkins scored 24 points on 9-for-17 shooting in 34 minutes off the Detroit bench. F/C Jalen Duren contributed 19 points (6-10 FG) and 14 rebounds for the Pistons. Make sure you know about how the fans are looking on social for Detroit with the Thrillz promo code.

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Bulls vs Pistons Pick

Detroit will be without F Isaiah Stewart (ankle), Ausar Thompson (ankle), and Tobias Harris (ankle) for this contest. These two teams are pretty evenly matched and the Pistons will be exhausted from Monday’s victory. Take the Bulls to pull off the upset on the road. Final Score Prediction, Chicago Bulls win 121-115. Make sure when you place your Bulls vs Pistons bet you are using the bet365 bonus code.