Cleveland Cavaliers vs Philadelphia 76ers Picks and Prediction for Wednesday January 14 2026

By: Eddie Kline Updated 01/21/2026, 02:44 PM ET

Cavaliers Preview

In the first game of a Wednesday night NBA on ESPN doubleheader, the Cleveland Cavaliers will battle the Philadelphia 76ers from the Wells Fargo Center. For other NBA action see our NBA Predictions. The Cavaliers (22-19) have split their previous ten games and trail Orlando by a half-game for sixth place in the Eastern Conference standings. On Monday, Cleveland was outscored by 19 points during the second half of a 123-112 home loss versus lowly Utah.

Dariius Garland led six Cleveland players in double figures with 23 points (7-17 FG) and eight assists. All-Star G Donovan Mitchell nailed 4-for-9 from long distance and finished with 21 points. Evan Mobley added 15 points, nine rebounds, and eight assists for the Cavaliers.

76ers Preview

The Philadelphia 76ers are a game above .500 at home and just a half-game out of fourth place in the Eastern Conference standings. The 76ers (22-16) rank eighth in the league in defensive efficiency and are allowing 115.2 points per contest. On Monday, Philadelphia raced out to a 17-point lead after one quarter and shot 53 percent from the field during a 115-102 road triumph against Toronto.

All-Star G Tyrese Maxey led all scorers with 33 points on 10-for-16 shooting and pulled down four boards. Philadelphia C Joel Embiid contributed 27 points (8-8 FT) and eight rebounds. Rookie G V.J. Edgecombe added 15 points and eight assists for the 76ers, who connected on 16-for-36 from long range.

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Cavaliers vs 76ers Pick

Philadelphia G V.J. Edgecombe is dealing with a left adductor contusion and is listed as probable for this contest. The 76ers are more connected on the defensive end of the floor and the Cavaliers have been inconsistent. Take Philadelphia to win at home. Final Score Prediction, Philadelphia 76ers win 123-115.

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