Indiana Pacers vs Boston Celtics Picks and Prediction for Wednesday January 21 2026

By: Eddie Kline Updated 01/21/2026, 02:41 PM ET

Pacers Preview

In Wednesday night NBA action, the Indiana Pacers will travel to TD Garden to take on the Boston Celtics. For other NBA action see our NBA Predictions. The Pacers (10-34) have dropped 18 of their first 20 road games and own the worst overall record in the Eastern Conference. On Monday, Indiana committed 22 turnovers during a 113-104 road loss against Philadelphia.

Andrew Nembhard led four Indiana players in double figures with 25 points on 9-for-15 shooting and dropped five dimes. All-Star F Pascal Siakam scored 24 points to go along with seven assists and six rebounds. Jay Huff added ten points, six rebounds, and three blocks for the Pacers.

Celtics Preview

The Boston Celtics have won 12 of their first 19 home games and are sitting in second place in the Eastern Conference standings. The Celtics (26-16) rank second in the league in offensive efficiency and are averaging 116.7 points per contest. On Monday, Boston missed 28 of 41 three-point attempts and shot 40 percent overall during a 104-103 road loss against Detroit.

All-Star G Jaylen Brown scored a game-high 32 points on 11-for-28 shooting and grabbed 11 rebounds. Payton Pritchard nailed half of his six long distance attempts and finished with 17 points. Sam Hauser added 16 points and five boards for the Celtics, who converted 24 of 30 from the charity stripe.

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Pacers vs Celtics Pick

Boston G Jaylen Brown is dealing with left hamstring tightness and is listed as probable for this game. The Pacers rank last in the league in offensive efficiency and the Celtics have a major advantage on the glass. Take Boston to cover at home. Final Score Prediction, Boston Celtics win 122-106.

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