San Antonio Spurs at New Orleans Pelicans Picks and Predictions for Friday, October 24, 2025

By: David Anicetti Published 10/24/2025, 12:05 AM ET

The San Antonio Spurs visit the New Orleans Pelicans at Smoothie King Center in New Orleans. The opening tipoff is at 8:00 PM ET on GCSEN. San Antonio (1–0) opened its season with a 125–92 win over Dallas. New Orleans (0–1) dropped its opener 128–122 in Memphis. These numbers come from each team’s first game of the season and are not averages. Shooting the game winner with our NBA picks.

San Antonio Spurs Preview

San Antonio looked sharp in its opener, shooting 57.5% from the floor and winning the rebounding battle 50–39. Victor Wembanyama dominated with 40 points, 15 rebounds, and three blocks in 30 minutes. Stephon Castle added 22 points and six assists on opening night, while Devin Vassell chipped in 13.

The Spurs took care of the ball and played fast, finishing with 24 assists to just 14 turnovers. If they control the paint again and get consistent touches for Wembanyama, they can win their second straight on the road.

New Orleans Pelicans Preview

New Orleans lost its opener but saw big production from Zion Williamson, who finished with 27 points, nine rebounds, and five assists. Herbert Jones, Jordan Poole, and rookie Jeremiah Fears each scored 17. The Pelicans built a halftime lead before giving up 41 points in the third quarter.

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The Pelicans must defend better and stay focused in transition. With several reserves out injured, New Orleans will need another strong showing from Williamson to keep up with San Antonio’s up-tempo pace and strong frontcourt.

San Antonio Spurs at New Orleans Pelicans Prediction

San Antonio’s size and interior scoring give it the upper hand, especially with New Orleans short-handed inside. The Spurs, behind second-year star Victor Wembanyama, will dictate the pace and win for a second time on the road. Final Score Prediction: San Antonio Spurs win and cover ATS 118-110.