San Antonio Spurs vs Dallas Mavericks Picks and Predictions for Wednesday, October 22, 2025

By: Cameron Ross Published 10/22/2025, 12:45 AM ET

San Antonio vs Dallas Information

The San Antonio Spurs will be on the road Wednesday night for a game in the American Airlines Center at 9:30 PM against the Dallas Mavericks to open the season. San Antonio comes into this season with high hopes, looking to improve on a 34-win season from a year ago. The Dallas Mavericks come into this year following an abysmal season last year. Dallas won just 39 games last season, but added depth to their roster and the number one overall pick in the draft. Stay in the loop with our NBA Picks.

Spurs Preview

Offensively, San Antonio was ranked 16th in the league a year ago, averaging 113.9 points per game overall. The San Antonio defense was an issue last year, ranking 23rd in the league, giving up 116.7 points per game. Victor Wembanyama led the show for the San Antonio offense a year ago, averaging 24.3 points and 11 rebounds per game, but played only 46 games. De’Aaron Fox averaged 19.7 points per game in 17 games played with San Antonio last year. Devin Vassell was third on the roster, averaging 16.3 points across 64 games played a season ago.

Mavericks Preview

The Dallas offense ranked 15th in the league last year, averaging 114.2 points per game overall. Defensively, Dallas was mediocre, ranking 20th in the league, giving up 115.4 points per game. Kyrie Irving led the way for the Dallas offense a year ago, averaging 24.7 points and 4.6 assists per game through 50 games played, but he will be out until 2026 due to an ACL injury. Anthony Davis averaged 20 points in 29.6 minutes across 9 games played last season for Dallas. PJ Washington averaged 14.7 points and led the team, pulling in 7.8 rebounds per game a year ago.

San Antonio vs Dallas Prediction

Dallas is the better team in this matchup, and it will show from Wednesday's opening minutes. Look for the Mavericks to open the season with a win and cover at home against a good San Antonio team. Take Dallas to do the work on Wednesday as they begin to turn the organization around after starting the year undefeated. Final Score Prediction, Dallas Mavericks win and cover 114-105

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