Dayton Flyers vs La Salle Explorers Picks and Prediction for Wednesday January 21 2026

By: Kim Smith Published 01/21/2026, 12:30 AM ET

The Dayton Flyers travel to Philadelphia to take on the La Salle Explorers at John Glaser Arena on Wednesday, January 21, 2026, with tipoff scheduled for 6:30 PM EST. This Atlantic 10 Conference matchup will be broadcast on ESPN+. At the time of this writing, the moneyline odds were not released for this game. The total is set at 137.5 points, with the Over priced at -115 and the Under at -105, while Dayton enters as a 10.5-point road favorite. Be sure to check out our free college basketball picks for more daily betting insight.

Flyers Flying High into Conference Play

Dayton comes into this matchup with a strong 14-4 overall record and has continued to build momentum during conference play. Over their last five games, the Flyers have recently won over Loyola Chicago twice, beaten Duquesne on the road, and picked up home victories against George Washington and Fordham, showing consistency on both ends of the floor.

From a statistical standpoint, Dayton is averaging 77.6 points per game while allowing just 68.1 points per contest. The Flyers are shooting 45% from the field and averaging 33 rebounds per game, reflecting a balanced offensive approach paired with solid defensive fundamentals.

One area where Dayton stands out is defensive activity. The Flyers average 9.8 steals and 4.2 blocks per game, creating extra possessions and disrupting opposing offenses. That defensive pressure has been a key factor in their recent winning streak.

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Explorers Look to Defend Home Court

La Salle enters Wednesday night with a 6-13 overall record and has struggled to find consistency this season. In their last five games, the Explorers have recently won at Rhode Island and defeated Saint Bonaventure at home, but they have also lost to Richmond, Saint Louis, and George Washington, highlighting ongoing issues against stronger conference opponents.

Offensively, La Salle is averaging 67.1 points per game while allowing 73.2 points per contest. The Explorers are shooting 42% from the field and pulling down 35.3 rebounds per game, but turnovers and defensive lapses have often put them in difficult positions.

La Salle’s lack of rim protection and defensive disruption has been noticeable, as they average just 2.6 blocks and 6.6 steals per game. Without consistent stops, the Explorers have struggled to slow down more efficient offensive teams.

Flyers vs Explorers Pick

Dayton Flyers vs La Salle Explorers Pick

Pick: Dayton -10.5

Dayton holds a clear edge in overall efficiency, defensive pressure, and recent form. The Flyers’ ability to force turnovers and convert those opportunities into points should create separation as the game progresses. Against a La Salle team that has struggled defensively, Dayton is well-positioned to cover the double-digit spread.

Dayton Flyers vs La Salle Explorers Total Pick

Pick: Under 137.5

I am taking the Under in this matchup because Dayton’s defense has consistently limited opponents’ scoring, and La Salle has struggled to generate offense against disciplined teams. With Dayton controlling tempo and emphasizing half-court execution, this game profiles as one that stays below the 137.5 total.

Final Score Prediction:

Dayton 72, La Salle 60

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