Howard vs Duke Picks and Prediction for Sunday, November 23, 2025

By: Jake Allman Published 11/23/2025, 12:35 AM ET

Howard heads into Cameron Indoor Stadium looking for a major upset against an unbeaten Duke team that has dominated every matchup so far. Duke sits at 6-0 and has rolled through its early schedule, averaging 93.7 points per game and giving up just 57.2. Howard comes in at 2-3 and has played several tight contests, including a four-point road loss at Stetson, where the offense stalled late. Both teams have strong individual scorers, but the overall gap in talent is clear to all. Big board, bigger value — see our winning college basketball predictions.

Howard Outlook

Howard relies heavily on Bryce Harris, who is carrying the offense at 22.4 points and 7.8 rebounds per game while shooting 54.5 percent from the field and 52.2 percent from three. Harris has been sharp in every game, and his combination of strong shooting and rebounding keeps Howard competitive when the pace picks up. The concern comes from the remainder of the roster, as the rest of the lineup has been inconsistent with turnovers and poor shooting. Howard averages 74.4 points per game on 46 percent shooting, but the team’s 15.4 assists and 14 turnovers show how thin the margin is when facing a top opponent. The best sportsbooks are the best way to go when you are betting on Howard.

Duke Outlook

Duke’s start has been overwhelming behind Cameron Boozer, who is putting up 20.3 points, 9.5 rebounds, and 4 assists per game while shooting just over 50 percent. Boozer controls tempo and spacing, and Duke builds around his scoring. The Blue Devils complement him with a strong set of teammates, including Isaiah Evans at 13.3 points per game and Patrick Ngongba at 12.5 points on a blistering 65.8 percent from the field. Duke’s regulars are performing well, which shows in the team’s 51 percent shooting and 20.7 assists per game. That ball movement has created open shots that have created big leads, including a 100-42 rout of Niagara and a 114-59 win over Army. Make sure you know about how the fans are looking on prediction markets for Duke with the Onyx Odds promo code.

Duke vs Howard Prediction

This matchup strongly favors Duke in pace, shot quality, and depth. Howard needs Harris to have a high-scoring night while also limiting turnovers, but Duke has not shown any weakness against teams that rely on a single scorer. The Blue Devils are too efficient in transition and too disciplined in the halfcourt to let this stay close for long. Getting the most out of your bets on Howard vs Duke can be done by using the Fanatics Sportsbook promo code.

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Prediction: Duke 96, Howard 63

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