Iowa State vs Purdue Picks and Predictions for Saturday, December 6, 2025

By: David Anicetti Published 12/06/2025, 01:35 AM ET

The Iowa State Cyclones visit the Purdue Boilermakers on Saturday. Iowa State is 8–0 after a 132–68 win over Alcorn State, while Purdue is 8–0 following an 81–65 victory at Rutgers. Build your bankroll with our free college basketball picks.

Iowa State vs Purdue Game Information

Date: December 6
Time: 12:00 PM ET
Where: Mackey Arena, West Lafayette, IN
TV: CBS

Breakdown - Iowa State Cyclones

Iowa State continues to showcase one of the nation’s strongest offenses, led by forward Joshua Jefferson, who is averaging 18.4 points, 7.3 rebounds, and 5.6 assists per game. Milan Momcilovic adds 18.1 points per game, giving the Cyclones another consistent scorer, while Tamin Lipsey contributes 18.4 points and 5.2 assists. Killyan Toure is averaging a team-high 2.2 steals per game, and Blake Buchanan provides interior help with 1.1 blocks per contest.

As a team, the Cyclones are averaging 96.3 points per game on 55.0% shooting from the field and 43.3% from three. Iowa State is also averaging 36.4 rebounds, 19.3 assists, and 11.8 steals per game, making them one of the most balanced teams in the nation entering December.

Breakdown - Purdue Boilermakers

Purdue continues to combine strong guard play with inside scoring, which has helped the Boilermakers remain unbeaten. Fletcher Loyer is averaging a team-high 15.6 points per game while shooting well from the perimeter, and Trey Kaufman-Renn is adding 15.5 points along with a team-leading 11.0 rebounds per game. Braden Smith directs the offense with a team-best 8.9 assists per outing and also leads the team in steals at 1.0 per game.

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The Boilermakers are averaging 88.6 points per game while shooting 51.0% from the floor and 41.8% from three. Purdue adds 40.9 rebounds, 20.6 assists, and 4.9 steals per outing, with Daniel Jacobsen contributing 2.4 blocks per game to anchor the interior.

Iowa State Cyclones vs Purdue Boilermakers Prediction

Iowa State has very strong shooting and scoring, but Purdue’s combination of interior strength, passing from the backcourt, and steady rebounding gives the Boilermakers the advantage at home. Iowa State’s perimeter production will keep the Cyclones competitive, but Purdue’s balance on both ends of the court will be the difference. Final Score Prediction: Purdue Boilermakers win and cover ATS, 84–76. Check out all the sportsbook promos to see if you are getting a great deal on your bets on Iowa State. Make sure you know about how the fans are looking on prediction markets for Purdue with the Kickr promo code. Make sure when you place your bet on Iowa State vs Purdue you are using the BetMGM bonus code.

Best Picks

• Purdue Boilermakers

• Over

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