Mississippi State vs Iowa State Picks and Prediction for Monday, November 10, 2025

By: Cameron Ross Published 11/10/2025, 01:15 AM ET

Mississippi State vs Iowa State Information

The Mississippi State Bulldogs take their first road trip of the year Monday night with a game in Sioux Falls, SD, against the Iowa State Cyclones. Mississippi State is undefeated through one game played, following a 24-point victory against North Alabama. The Iowa State Cyclones are the 16th-ranked team in the nation, undefeated through two games after a 40-point blowout of Grambling in the second game of the season. Stay in the action with our College Basketball Picks.

Mississippi State Preview

Offensively, Mississippi State was solid in game one of the season, pouring in 86 points on 43.7% shooting from the floor. Defensively, the Bulldogs did the job, giving up 62 points and pulling in 53 rebounds in the win. Josh Hubbard led the way for Mississippi State in game one of the season, boasting a team-high 27 points and eight assists. Ja’Borri McGhee was 2nd on the team with 14 points, and Quincy Ballard chipped in a third-best eight points in 20 minutes.

Iowa State Preview

The Iowa State Cyclones offense has been the team's biggest strength this season, averaging 95 points on 53.4% shooting after scoring 102 points in game two of the year. Defensively, Iowa State has been just as strong, holding opponents to 56 points per game overall. Milan Momcilovic leads Iowa State this season, averaging 20 points per game. Joshua Jefferson is second on the roster, averaging 17 points, and boasts a team-high 9 rebounds per game. Tamin Lipsey averages a third-best 14 points and leads the team, averaging 5.5 assists per game.

Mississippi State vs Iowa State Prediction

Both teams are undefeated coming into this matchup, but Iowa State has the edge. Look for the Cyclones to dominate this game, start to finish, as they continue their winning ways. Take Iowa State Monday night in South Dakota to get the win and cover against Mississippi State. Final Score Prediction, Iowa State Cyclones win and cover 87-73.

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