Missouri vs Illinois Picks and Predictions for Monday, December 22, 2025

By: Cameron Ross Published 12/22/2025, 02:45 AM ET

Missouri vs Illinois Information

The Missouri Tigers will be in St. Louis, MO, on Monday at 8:00 PM to face the Illinois Fighting Illini. Missouri has 10 wins and two losses this season, coming into Monday having won 3 of the last five following the 22-point victory against Bethune-Cookman. The Illinois Fighting Illini come into Monday ranked #18 in the nation with eight wins and three losses, following a 3-point loss to Nebraska in their last outing that ended a 2-game winning streak. Stay in the news with our College Basketball Picks.

Missouri Preview

Missouri has scored well this season, averaging 86.8 points on 54% from the floor. Defensively, the Tigers have been even better, holding opponents to 69.8 points per game through 12 games played. Mark Mitchell leads the Missouri offense this season, averaging 18.1 points and 6.1 rebounds per game. Jacob Crews averages 14.8 points, and Jayden Stone averages 13.3 points per game. Anthony Robinson II averages 10.8 points and leads Missouri, averaging 3.7 assists per game.

Illinois Preview

Offensively, Illinois has scored the ball well this season, averaging 87.8 points on 40% shooting from the floor. Defensively, Illinois has been just as strong, holding opponents to 71.5 points per game, but it allowed 83 in its most recent loss to Nebraska. Kylan Boswell leads the Illinois offense this season, averaging 16.1 points and 3.5 assists per game. Andrej Stojakovic averages 15.5 points, and Keaton Wagler is third on the team, averaging 15.1 points per game.

Missouri vs Illinois Prediction

Both teams are having solid seasons coming into this game, but Illinois is the better team. Look for the Fighting Illini to use their depth and talent to overwhelm a good Missouri team. Take Illinois to bounce back from their recent loss as they get the win and cover in Saint Louis against Missouri. Final Score Prediction, Illinois Fighting Illini win and cover 78-70. Make sure you know about how the fans are looking on prediction markets for Missouri with the Fliff promo code. The best sportsbooks are the best way to go when you are betting on Illinois. Make sure when you place your Illinois vs Missouri bet you are using the bet365 bonus code.

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