Northwestern vs DePaul Picks and Predictions for Friday, November 14, 2025

By: Cameron Ross Published 11/14/2025, 01:40 AM ET

Northwestern vs DePaul Information

The Northwestern Wildcats will be on the road for the first time this season Friday night, facing the DePaul Blue Demons in Chicago at 8:30 PM. Northwestern is undefeated through three games played coming into this matchup following a 47-point victory in their last outing. The DePaul Blue Demons stay at home Friday night with two wins and one loss after a 13-point home loss to Buffalo last time. Stay in the loop with our College Basketball Picks.

Northwestern Preview

Offensively, Northwestern has been solid all season, averaging 85.3 points on 50.6% shooting from the floor, to score 110 points in their last outing. Defensively, the Wildcats have been even better, holding opponents to 54 points per game. Nick Martinelli leads the Northwestern offense this season, averaging 19.3 points per game. Jayden Reid is third on the roster, averaging 10.3 points, and boasts a team-leading 6.3 assists. Arrenton Page is second on the team, averaging 14 points to go along with a team-high 9.3 rebounds per game. The best sportsbooks are the best way to go when you are betting on Northwestern.

DePaul Preview

Offensively, DePaul has been mediocre this season, averaging 72.3 points on 40.5% shooting from the floor. Defensively, the Blue Demons have been solid, holding opponents to 64 points per game overall this season, despite giving up 66 in their loss last time out. CJ Gunn leads the DePaul offense this season, averaging 15.7 points per game. NJ Benson is second on the roster, averaging 14.3 points to go along with the team-leading 9.3 rebounds. Layden blocker averages 8 points and boasts a team high 4.3 assists. Make sure you know about how the fans are looking on prediction markets for DePaul with the Onyx Odds promo code.

Northwestern vs DePaul Prediction

Both teams are having solid seasons heading into this matchup, but Northwestern will do the job Friday night. Look for the Wildcats to establish themselves early as they overwhelm a good DePaul team. Take Northwestern to get the win and cover on the road as they remain undefeated following a win in Chicago. Final Score Prediction, Northwestern Wildcats win and cover 78-70. Getting the most out of your bets on Northwestern vs DePaul can be done by using the Fanatics Sportsbook promo code.

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