Notre Dame Fighting Irish vs Louisville Cardinals Picks and Prediction for Wednesday, February 4, 2026
The Notre Dame Fighting Irish will visit the Louisville Cardinals on Wednesday night. Notre Dame is 11-11 overall and 2-7 in ACC play, sitting 14th in the conference standings after an 86-72 road loss at Syracuse. Louisville is 15-6 overall and 5-4 in ACC action, currently 8th in the conference standings, coming off an 88-74 home win over SMU. Create a winning ticket with our free college basketball picks.
Game Information
- Date: Wednesday, February 4
- Time: 7:00 PM ET
- Location: KFC Yum! Center, Louisville, KY
- TV: ESPN2
Notre Dame Fighting Irish Outlook
Notre Dame averages 74.0 points per game while allowing 72.2, often struggling to generate consistent offense when forced into extended half-court possessions. Jalen Haralson leads the Irish at 15.5 points per game. Carson Towt provides interior presence, averaging 9.5 rebounds per game, helping Notre Dame stay competitive on the glass despite size disadvantages.
Ball movement has been a challenge, with the Irish averaging just 12.0 assists per game, limiting scoring opportunities when forced into half-court sets. The defense has struggled, as Notre Dame averages only 4.3 steals and 2.1 blocks per game. Notre Dame does not have any players listed on its injury report.
Key Stats – Per Game
- Points: 74.0
- Points Allowed: 72.2
- Rebounds: 37.1
- Assists: 12.0
- Steals: 4.3
- Blocks: 2.1
- Turnovers: 11.5
Louisville Cardinals Outlook
Louisville has the better offense in this matchup, averaging 86.1 points per game while holding opponents to 70.5. Ryan Conwell leads the Cardinals with an average of 19.1 points per game and serves as the primary scoring threat from the perimeter. Sananda Fru averages 10.2 points, 6.7 rebounds, and 1.3 blocks per game, giving Louisville a reliable interior presence on both ends.
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The Cardinals average 17.6 assists per game, helping Louisville to perform well both in transition and half-court sets. Louisville also controls the glass well, averaging 40.4 rebounds per game, and protects the rim with 3.3 blocks per contest. Louisville does not have any players listed on its injury report.
Key Stats – Per Game
- Points: 86.1
- Points Allowed: 70.5
- Rebounds: 40.4
- Assists: 17.6
- Steals: 7.3
- Blocks: 3.3
- Turnovers: 11.5
Notre Dame Fighting Irish vs Louisville Cardinals Prediction
Louisville’s advantages in scoring balance, rebounding, and assists set the tone for this matchup. Notre Dame’s limited offense will make it difficult to remain close for the full game. By controlling the glass and limiting turnovers, the Cardinals will pull away early and win big at home. Final Score Prediction: Louisville Cardinals win and cover ATS, 89-69.
Best Picks
- Louisville Cardinals
- Over
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