Notre Dame vs Houston Picks and Predictions for Wednesday, November 26, 2025

By: Cameron Ross Published 11/26/2025, 11:21 AM ET

Notre Dame vs Houston Information

The Notre Dame Fighting Irish continue a road trip in Las Vegas on Wednesday with a 3:30 PM matchup against the Houston Cougars. Notre Dame has five wins and two losses coming into Wednesday, following a 5-point victory against Rutgers on Tuesday. The Houston Cougars are the number 3-ranked team in the nation with six wins and one loss overall following a three-point loss to Tennessee Tuesday night. Stay in the action with our College Basketball Picks.

Notre Dame Preview

Offensively, Notre Dame has scored the ball well this season, averaging 79.8 points on 48% shooting from the floor. Defensively, Notre Dame has been phenomenal, allowing 67.4 points per game this season, and gave up only 63 in their victory over Rutgers on Tuesday. Markus Burton leads the Notre Dame offense this season with 20.2 points per game. Jalen Haralson is second on the team with 12.6 points, and Braeden Shrewsberry averages a third-best 11 points per game. Carson Towt averages 6.7 points per game and leads Notre Dame, pulling in 12.2 rebounds and dishing out 2.5 assists.

Houston Preview

Offensively, Houston has been mediocre this season, averaging 76.3 points on 44% shooting from the floor. Defensively, Houston is one of the best teams in the nation, allowing 59.6 points per game this season, but gave up 76 in their loss to Tennessee on Tuesday. Emanuel Sharp leads the Houston offense this season, averaging 17.7 points per game. Freshman Kingston Flemings is second on the team, averaging 16 points, to go along with a team-leading 5.3 assists. Milos Uzan averages 11.8 points in just over 32 minutes per game. Chris Cenac Jr. averages 10.5 points and leads Houston, pulling in 8.2 rebounds per contest.

Notre Dame vs Houston Prediction

Houston is the better team in this matchup and will bounce back on Wednesday. Look for the Cougars’ defense to stifle Notre Dame for 40 minutes, resulting in the victory. Take Houston to use their strengths Wednesday night to get the win and cover in Las Vegas against Notre Dame. Final Score Prediction, Houston Cougars win and cover 74-64.

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